Depression Clinical Trials

Showing 121-140 of 3,654 trials

Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder

NCT04133233

The purpose of this study will be to demonstrate improvement of the T regulatory cells (Treg) response, under add on low-dose Interleukin 2 (ld-IL2) in patients with bipolar disorders experiencing a depressive relapse

Bipolar Depression

Assistance Publique - Hôpitaux de Paris14 participantsStarted Jun 2020

Créteil, Hôpital Albert Chenevier, France

RECRUITINGNA

Implementing Depression and Adherence Treatment

NCT07032363

The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression. The main questions it aims to answer are: What proportion of patients start an evidence-based treatment for depression (reach)? What percentage of patients show clinical improvement in depression and what percentage attain viral undetectability within one year (effectiveness)? Researchers will compare high and low reach clinics to further inform tailored implementation strategies for uptake and maintenance. Clinics will be randomized into one of two study arms: core versus enhanced strategies. In both arms, core strategies will be utilized. Enhanced clinics will also receive more resource-intensive training.

DepressionHIVAdherence, Treatment+1 more

University of Miami10 participantsStarted Apr 2026

Miami, Florida, United States • Boston, Massachusetts, United States • Cape Town, South Africa

Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder

Implementing Depression and Adherence Treatment

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