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Clareo Health | Depression Clinical Trials in Houston | 165 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 165 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 165 trials

CompletedTrial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive DisorderThis is a phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-arm trial to assess the efficacy, safety, and tolerability of centanafadine once-daily (QD)…NCT05536414·Yuma, Arizona and 61 others

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Data from ClinicalTrials.govTerms

Active not recruiting"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"The purpose of this study is to examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with MDD.NCT06564818·Phoenix, Arizona and 44 others

CompletedEfficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in Combination With an Antidepressant in the Treatment of Major Depressive DisordersThe purpose of this study is to evaluate the efficacy of quetiapine SR in combination with an antidepressant versus an antidepressant alone in patients with MDD with inadequate…NCT00326105·Phoenix, Arizona and 55 others

TerminatedExtension Study of Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant TreatmentTo assess the safety and tolerability of long-term pimavanserin treatment in subjects with major depressive disorder and inadequate response to antidepressant treatment.NCT04000009·Garden Grove, California and 70 others

CompletedAV-101 as Adjunct Antidepressant Therapy in Patients With Major DepressionThe study will evaluate the safety and efficacy of AV-101.NCT03078322·Garden Grove, California and 21 others

CompletedSafety and Efficacy of Vilazodone in Major Depressive DisorderSafety and Efficacy of Vilazodone in Major Depressive DisorderNCT01573598·Beverly Hills, California and 74 others

CompletedStudy to Evaluate Potential Predictors of Relapse in Participants With Major Depressive Disorder (MDD)The purpose of this study is to identify if there are self-reported or objective measures related to mood parameters that can predict near-term relapse (within 1 month or at…NCT02489305·Birmingham, Alabama and 24 others

CompletedA Long-Term Safety Study of ALKS 5461This is a 52-week open-label study to evaluate the safety and tolerability of ALKS 5461.NCT02141399·Birmingham, Alabama and 157 others

CompletedEfficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in the Treatment of Major Depressive DisordersThe purpose of this study is to demonstrate superior efficacy of Quetiapine fumarate sustained release (SEROQUEL) compared with placebo when used as a mono-therapy in the…NCT00326144·Phoenix, Arizona and 33 others

CompletedA Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-03)This study will evaluate the efficacy, safety, and tolerability of rapastinel 450 milligrams (mg) compared to placebo adjunctive to antidepressant therapy (ADT) in patients with…NCT02943577·Dothan, Alabama and 39 others

TerminatedA Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.The purpose of this study is to assess the safety and effect of TC-5214 as a single therapy in patients with major depressive disorder who exhibit inadequate response to…NCT01288079·Beverly Hills, California and 62 others

RecruitingDBS for DepressionThe goal of the study is to address the unmet need of TRD patients by identifying brain networks critical for treating depression and to use next generation precision DBS with…NCT03437928·Dallas, Texas and 1 other

Active not recruitingDeep Brain Stimulation (DBS) Therapy for Treatment Resistant DepressionWe propose a clinical study of medial forebrain bundle DBS as a treatment in 20 patients with treatment refractory depression (TRD).NCT02046330·Houston, Texas

CompletedSafety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)To assess the long-term safety and tolerability of oral OPC-34712 (brexpiprazole), given in addition to an FDA approved antidepressant (ADT) for the treatment of adults with Major…NCT01360866·Birmingham, Alabama and 141 others

CompletedGenomics Used to Improve DEpression DecisionsEvaluate the impact of GeneSight Psychotropic on response to psychotropic treatment as judged by the mean change in the 17-item Hamilton Depression (HAM-D17) score from baseline…NCT02109939·Birmingham, Alabama and 60 others

CompletedAdjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant TreatmentTo evaluate the efficacy and safety of adjunctive pimavanserin compared to placebo in subjects with major depressive disorder who have an inadequate response to antidepressant…NCT03968159·Birmingham, Alabama and 84 others

CompletedEfficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive DisorderThe purpose of this study is to evaluate the effects of Lu AA21004, once daily (QD), on cognitive dysfunction in patients with major depressive disorder.NCT01564862·Tucson, Arizona and 91 others

CompletedEfficacy, Safety and Tolerability of Agomelatine Sublingual Tablets in the Treatment of Major Depressive Disorder (MDD)The study will assess efficacy, safety and tolerability of 0.5 mg/day and 1 mg/day of sublingual (under the tongue) formulation of agomelatine in patients with Major Depressive…NCT01110902·Birmingham, Alabama and 44 others

CompletedStudy to Evaluate the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive DisorderThis is a randomized, double blind, placebo controlled, multi-center study to evaluate the effects of NMRA-335140 (formerly BTRX 335140) on symptoms of depression in participants…NCT06029426·Huntsville, Alabama and 63 others

CompletedA Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive DisorderThe primary purpose of this study is to evaluate the efficacy of SAGE-217 plus an ADT in the treatment of major depressive disorder (MDD) compared to placebo plus an ADT.NCT04476030·Dothan, Alabama and 50 others

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