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Clareo Health | Depression Clinical Trials in Chicago | 177 Studies

Clinical Trials DepressionChicago

Depression Clinical Trials in Chicago

Find 177 clinical trials for depression near Chicago, Illinois. Connect with research centers in your area.

All Depression trials nationwide All trials in Chicago

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 177 trials

TerminatedA Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant TherapyThe purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in…NCT04532749·Phoenix, Arizona and 79 others

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Data from ClinicalTrials.govTerms

CompletedStudy of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy VolunteersThe purpose of this study is to assess the safety and tolerability of multiple oral (PO) ascending doses of NRX-1074 in normal healthy volunteers.NCT02366364·Chicago, Illinois

CompletedTrial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive DisorderThis is a phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-arm trial to assess the efficacy, safety, and tolerability of centanafadine once-daily (QD)…NCT05536414·Yuma, Arizona and 61 others

Active not recruiting"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"The purpose of this study is to examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with MDD.NCT06564818·Phoenix, Arizona and 44 others

TerminatedExtension Study of Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant TreatmentTo assess the safety and tolerability of long-term pimavanserin treatment in subjects with major depressive disorder and inadequate response to antidepressant treatment.NCT04000009·Garden Grove, California and 70 others

CompletedSynchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive DisorderThis study is designed to evaluate the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) using the NeoSync EEG Synchronized TMS device (NEST) in…NCT01370733·Los Angeles, California and 17 others

RecruitingA Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With DepressionIn this study, researchers will learn more about a study drug called DT-101 in participants with Major Depressive Disorder (MDD), a form of depression.NCT07610473·Phoenix, Arizona and 22 others

CompletedStudy to Evaluate Potential Predictors of Relapse in Participants With Major Depressive Disorder (MDD)The purpose of this study is to identify if there are self-reported or objective measures related to mood parameters that can predict near-term relapse (within 1 month or at…NCT02489305·Birmingham, Alabama and 24 others

CompletedOnabotulinumtoxinA as Treatment for Major Depressive Disorder in Adult FemalesThis study will evaluate the safety and efficacy of onabotulinumtoxinA (BOTOX®) compared with placebo as treatment for major depressive disorder (MDD) in adult females.NCT02116361·Little Rock, Alaska and 34 others

CompletedMood Effects of Serotonin Agonists: DepressionThis study will examine the effect of a low dose of the 5HT2A agonist LSD (26 µg), compared to placebo, on acute and protracted mood states in individuals with depression.NCT07017478·Chicago, Illinois

Active not recruitingPsilocybin for Major Depressive Disorder (MDD)Approximately 240 eligible adult participants (≥18 years old) who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) criteria for Major Depressive Disorder…NCT06308653·Birmingham, Alabama and 28 others

CompletedA Long-Term Safety Study of ALKS 5461This is a 52-week open-label study to evaluate the safety and tolerability of ALKS 5461.NCT02141399·Birmingham, Alabama and 157 others

CompletedA Study of Intermittent Doses of CERC-301 in MDDThere is a significant unmet medical need for rapidly acting treatment of subjects with severe major depressive disorder (MDD) who have not adequately responded to antidepressant…NCT02459236·Newport Beach, California and 12 others

CompletedSafety and Efficacy of Vilazodone in Major Depressive DisorderThe purpose of this study was to evaluate the efficacy, safety, and tolerability of 2 fixed dose levels of vilazodone compared to placebo in patients with major depressive…NCT01473381·Birmingham, Alabama and 53 others

TerminatedStudy to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)This will be a multicenter, randomized, double-blind study designed to assess the efficacy, safety and tolerability of an oral Aripiprazole/Escitalopram combination therapy in…NCT01111539·Cerritos, California and 61 others

CompletedGenomics Used to Improve DEpression DecisionsEvaluate the impact of GeneSight Psychotropic on response to psychotropic treatment as judged by the mean change in the 17-item Hamilton Depression (HAM-D17) score from baseline…NCT02109939·Birmingham, Alabama and 60 others

TerminatedTreatment of Major Depressive Disorder With Psychotic Features.The purpose of this study is to determine the safety and efficacy of risperidone monotherapy in the treatment of psychotic depression.NCT00174590·Chicago, Illinois

CompletedAdjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant TreatmentTo evaluate the efficacy and safety of adjunctive pimavanserin compared to placebo in subjects with major depressive disorder who have an inadequate response to antidepressant…NCT03968159·Birmingham, Alabama and 84 others

CompletedEfficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive DisorderThe purpose of this study is to evaluate the effects of Lu AA21004, once daily (QD), on cognitive dysfunction in patients with major depressive disorder.NCT01564862·Tucson, Arizona and 91 others

WithdrawnAntidepressant Effects of Nitrous OxideTo evaluate the acute and sustained antidepressant effects of nitrous oxide in people with major depressive disorder; and further evaluate these effects by identifying the optimal…NCT05357040·Chicago, Illinois and 1 other

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