Depression Clinical Trials

Showing 1021-1040 of 1,725 trials

Improving Quality of Life in Early Parkinson's Disease

NCT04590612

The study will examine 30 patients between ages 50-80, newly diagnosed with early-stage Parkinson's Disease. Patients will be randomized to receive either Citalopram or Carbidopa-levodopa. The investigators' primary outcome measure will be change in quality of life over a prospective period of 6 months. Secondary outcome measures will include change in mood state and motor symptoms, as well as comparison of improvement between two treatments. Primary investigators would also like to collect quantitative electroencephalogram (qEEG) recordings, which is a reading of brain activity as an additional interest of this study. Primary investigators will assess the qEEG recordings for electrophysiological findings before and after interventions.

Parkinson DiseaseDepression

Western University, Canada30 participantsStarted Jan 2021

COMPLETEDPhase 2

Adjunct Minocyline in Treatment-resistant Depression

NCT02456948

This study examines the antidepressant efficacy of minocycline as an adjunct to an antidepressant standard treatment (AD-ST), for patients with unipolar major depressive disorder (MDD).

Major Depressive Disorder

Charite University, Berlin, Germany168 participantsStarted Jan 2015

Heidelberg, Baden-Wurttemberg, Germany • Erlangen, Bavaria, Germany • Munich, Bavaria, Germany +6 more locations

Improving Quality of Life in Early Parkinson's Disease

Adjunct Minocyline in Treatment-resistant Depression

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