Clareo Health | An Eight-week Study Evaluating the Efficacy of a 100mg Dose of Saredutant Once Daily, in Elderly Patients With Major Depressive Disorder
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sanofi
Age
60–64
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of major depressive disorder, recurrent, as defined by Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revision (DSM-IV-TR) criteria (296.3) and confirmed by the semi-structured Mini International Neuropsychiatric Interview (MINI).
You may not be if
Total score of less than 23 on the MADRS.
HAM-D total score less than 17.
Duration of the current depressive episode less than 1 month or greater than 2 years.
Patients with an Mini Mental State Examination score of less than 23.
Patients with a history or presence of bipolar disorders or psychotic disorders.
Patients with alcohol/substance dependence or abuse in the past 12 months except nicotine or caffeine dependence.
Patients who have used the following prior to entry into Acute Phase: antipsychotics within 3 months, fluoxetine within 1 month, monoamine oxidase inhibitors within 4 weeks, other antidepressants, or mood-stabilizer (lithium, anticonvulsants) within 1 week.
The investigator will evaluate whether there are other reasons why a patient may not participate
