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Clareo Health | Depression Clinical Trials in Philadelphia | 174 Studies

Clinical Trials DepressionPhiladelphia

Depression Clinical Trials in Philadelphia

Find 174 clinical trials for depression near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Depression trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 174 trials

CompletedMulticomponent Yoga Intervention for Major Depressive DisorderThe purpose of this study is to evaluate the efficacy of a multi-component yoga intervention featuring Sudarshan Kriya Yoga (SKY) as an adjunctive treatment for patients with…NCT02616549·Philadelphia, Pennsylvania CompletedA Long-Term Study of Aripiprazole in Patients With Major Depressive DisorderThis trial is a 52-week safety study to evaluate the safety of adjunctive aripiprazole in outpatients with major depressive disorder who have experienced an incomplete response to…NCT00095745·Mesa, Arizona and 57 others

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Data from ClinicalTrials.govTerms

CompletedSafety and Efficacy of Vortioxetine (Lu AA21004) in Adults With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy, safety and tolerability of vortioxetine, once daily (QD), compared with placebo in adults with major depressive disorder.NCT01153009·Beverly Hills, California and 55 others

CompletedStudy of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial)To compare the effect of OPC-34712 (brexpiprazole) to the effect of placebo (an inactive substance) as add on treatment to an assigned FDA approved antidepressant treatment (ADT)…NCT01360645·Arcadia, California and 56 others

CompletedA Comparison of Tolerability and Efficacy of Different Doses of Duloxetine for the Treatment of Major Depressive DisorderThe purpose of this study is to compare the tolerability and efficacy of different doses of duloxetine in patients with major depressive disorder.NCT00191061·Little Rock, Arkansas and 31 others

CompletedA Paroxetine- and Placebo-Controlled Study of 50 mg/Day and 100 mg/Day of EB-1010 Among Outpatients With Major Depressive Disorder Who Have Responded Inadequately to Prior Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)The main research hypothesis for this study is that, among patients with Major Depressive Disorder (MDD) who have responded inadequately to treatment with SSRIs or SNRIs, the…NCT01318434·Arcadia, California and 42 others

CompletedSafety and Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy, safety and tolerability of vortioxetine, once daily (QD), compared with placebo in adults with major depressive disorder.NCT01179516·Little Rock, Arkansas and 60 others

CompletedEfficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive DisorderThis study will assess efficacy, safety and tolerability of agomelatine (AGO178) 25 mg and 50 mg in patients with Major Depressive Disorder (MDD).NCT00411242·Mesa, Arizona and 50 others

CompletedSafety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo and Active Control in Major Depressive DisorderThis study is to evaluate that (SEROQUEL®) quetiapine sustained-release is efficacious and safe in the treatment of patients with MDD.NCT00321490·Birmingham, Alabama and 33 others

CompletedA Study of Adjunctive Aripiprazole in Patients With Major Depressive DisorderThis trial is a 14 week, randomized, double-blind, placebo controlled study, to assess the safety and efficacy of aripiprazole as adjunctive treatment to an ongoing antidepressant…NCT00095823·Garden Grove, California and 19 others

CompletedFeasibility of a Behavioral Activation TrialThe goal of this project is to train community mental health therapists in behavioral activation (BA) treatment for major depressive disorder and then to conduct a study examining…NCT02992158·Philadelphia, Pennsylvania

CompletedA Study to Evaluate ALKS 5461 in Subjects With Major Depressive Disorder (MDD)This study will evaluate the efficacy of ALKS 5461 when administered daily for 4 weeks to adults with Major Depressive Disorder (MDD) and inadequate response to antidepressant…NCT01500200·Tucson, Arizona and 26 others

Enrolling by invitationPhase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)This is a long- term extension of the double-blind trials APPROACH (CYB003-002) and EMBRACE (CYB003-003).NCT06605105·Phoenix, Arizona and 48 others

CompletedA United States Study of Corlux for Psychotic Symptoms in Psychotic Major DepressionCorlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol.NCT00130676·Pico Rivera, California and 22 others

Active not recruitingGetting Out of the House: Using Behavioral Activation to Increase Community ParticipationThe goal of this study is to evaluate the effectiveness of an behavioral activation intervention to increase meaningful activity and community participation for people with…NCT06336616·Philadelphia, Pennsylvania

RecruitingDecoding and Modulating Affective Brain StatesThe research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial…NCT05437705·Philadelphia, Pennsylvania

CompletedA Safety Study in Participants With Major Depressive DisorderThe primary objective of this study is to evaluate the long-term safety and tolerability of LY2216684 administered once daily (QD) in the adjunctive treatment with a selective…NCT01155661·Birmingham, Alabama and 47 others

CompletedA Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With SeltorexantThe purpose of this study is to assess the efficacy of seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in…NCT04533529·Anaheim, California and 121 others

RecruitingA Randomized Study of Azetukalner Versus Placebo in Major Depressive DisorderX-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy…NCT06775379·Phoenix, Arizona and 50 others

CompletedSafety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive DisorderAn outpatient study to evaluate the safety and efficacy of cariprazine as adjunct to antidepressant therapy (ADT) in participants with major depressive disorder (MDD) who have an…NCT01469377·Garden Grove, California and 71 others

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