About Pricing FAQs Providers Trials Blog

Login Get started

Finding studies

Your health journey, clearly organized.

Questions? feedback@clareohealth.com

Product

How it works
Pricing
For Providers
Trials

Company

About
Blog
FAQ

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Clinical TrialsDepression

Depression Clinical Trials

Browse 3,199 clinical trials for depression. Find studies that match your criteria and connect with research centers.

Find trials near:

New York Los Angeles Chicago Houston Phoenix Philadelphia

Order

Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

Healthy volunteers too

Showing 1-20 of 3,199 trials

CompletedSupported Employment in Patient Aligned Care TeamsIn response to the Rehabilitation Research and Development (RR\&D) Deployment Health Research, this study addresses the delivery of an evidenced-based vocational rehabilitation…NCT02400736·Tuscaloosa, Alabama CompletedA Study of LY2216684 in Participants With Major Depression DisorderThe primary objective of this study is to evaluate the long-term safety and tolerability of LY2216684 administered once daily in the adjunctive treatment with an Selective…NCT01370499·Chiba and 8 others

Related Searches

major depressivetrials mddtrials

Data from ClinicalTrials.govTerms

CompletedD-serine Supplementation for DepressionThe glutamate system is emerging as target for the development of novel antidepressant medication, in particular compounds modulating the NMDA receptor.NCT04721249·Basel, Canton of Basel-City

RecruitingSleep TMS for DepressionThe goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in…NCT06824415·Stanford, California

UnknownAcupuncture for Patients With Major Depressive DisorderSeveral studies investigating acupuncture for major depressive disorder (MDD) have been carried out.NCT05106868

TerminatedA Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant TherapyThe purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in…NCT04532749·Phoenix, Arizona and 79 others

Active not recruitingMindfulness Engaged Neurostimulation for DepressionRepetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the…NCT06399406·La Jolla, California

CompletedDBS for Treatment Resistant DepressionThe purpose of this study is to examine the effects of sub-callosal cingulate (SCC) deep brain stimulation (DBS) in patients with treatment resistant depression (TRD).NCT01983904·Calgary, Alberta

TerminatedComparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With DepressionThis study focuses on treating adolescents with depression. The study has two main purposes.NCT01740726·Atlanta, Georgia

RecruitingAt-Home tDCS as Maintenance TherapyThe primary purpuse of this pilot study is to find out whether a home-based transcranial direct current stimulation (tDCS) program is feasible and well tolerated as maintenance…NCT07269964·München, Bavaria and 1 other

CompletedStudy of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy VolunteersThe purpose of this study is to assess the safety and tolerability of multiple oral (PO) ascending doses of NRX-1074 in normal healthy volunteers.NCT02366364·Chicago, Illinois

WithdrawnVortioxetine in Patients With Major Depressive Disorder and Coronary Artery DiseaseThis is a preliminary, open-label, clinical trial designed to assess the efficacy, safety, and tolerability of vortioxetine for the treatment of major depressive disorder in…NCT02454426·Philadelphia, Pennsylvania

CompletedComparing Group Therapies for Veterans With Depression and PTSDCognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and PTSD.NCT03979040·Charleston, South Carolina

CompletedCollaborative Depression Care Management in Treating Depressed Low-income Hispanics With DiabetesThis study will evaluate the effectiveness of culturally adapted depression treatment for reducing depressive symptoms and improving adherence to diabetes self-care regimens in…NCT00709150·Los Angeles, California

CompletedA Qualitative Analysis of Youth Responses to Depression Education Delivered on Social MediaDepression is a common mental disorder among adolescents, with increased rates during the COVID-19 pandemic.NCT07100548·Munich, Bavaria

RecruitingPeripheral Neuroimmune Mechanisms of HyperthermiaThe goal of this study is to examine how whole-body hyperthermia affects the thermoinflammatory profile, which includes the combined immune and heat shock response, in patients…NCT05366270·Boston, Massachusetts

CompletedSafety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant AnxietyThe purpose of this study is to determine whether BCI-540 80 mg given once daily (q.d.) or three times daily (t.i.d.) is effective in the treatment of major depression with…NCT00621270·Edmonton, Alberta and 15 others

Active not recruitingEMA-Guided Maintenance TMS for DepressionThe goal of this study is to evaluate the use of ecological-momentary-assessment (EMA) as a method for scheduling maintenance treatments for patients with Major Depressive…NCT06145594·Providence, Rhode Island

CompletedSedating Antidepressant Improves Driving Safety in Patients With Major Depressive DisorderThis concurrent, two-part study will: I) Using overnight sleep recordings, evaluate the short- and long-term sleep-promoting effects of the antidepressant mirtazapine (Remeron)…NCT00385437·Toronto, Ontario

CompletedPUFA Augmentation in Treatment of Major DepressionThe purpose of this study is to determine if omega-3 fatty acid EPA will enhance and speed up response to antidepressant therapy with Celexa (Citalopram) in people suffering from…NCT00067301·Los Angeles, California

Page 1 of 160Next

Clareo Health | Depression Clinical Trials | 3,199 Studies Recruiting