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Clareo Health | Depression Clinical Trials in Philadelphia | 174 Studies

Clinical Trials DepressionPhiladelphia

Depression Clinical Trials in Philadelphia

Find 174 clinical trials for depression near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Depression trials nationwide All trials in Philadelphia

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 101-120 of 174 trials

RecruitingPhase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia SymptomsThe purpose of this study is to know how well seltorexant works, and also to evaluate safety and maintenance effect of seltorexant compared with placebo as an adjunctive therapy…NCT06559306·Birmingham, Alabama and 204 others

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Data from ClinicalTrials.govTerms

CompletedStudy of a Repetitive Transcranial Magnetic Stimulation (rTMS) Device for the Treatment of Major Depressive DisorderThis trial will test the safety and efficacy of a rTMS device for the treatment of major depressive disorder (MDD). It is hypothesized that rTMS will have an antidepressant effect.NCT00104611·Poway, California and 12 others

CompletedStudy of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive DisorderPrimary: To compare the efficacy of OPC-34712 to placebo as adjunctive treatment to an assigned open-label marketed antidepressant treatment (ADT)in patients who demonstrate an…NCT00797966·Arcadia, California and 49 others

CompletedComparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRDThis is a multi-site, randomized, open-label, effectiveness trial comparing three treatment arms for Major Depressive Disorder (MDD) patients with TRD who are currently on…NCT02977299·Birmingham, Alabama and 12 others

CompletedEscitalopram in Adult Patients With Major Depressive DisorderThis is a short-term study to evaluate the efficacy, safety, and tolerability of escitalopram in adult patients (18 to 65 years of age) with moderate to severe depression.NCT00668525·Phoenix, Arizona and 44 others

CompletedThe Safety and Efficacy of Escitalopram in Pediatric Patients With Major Depressive DisorderDepression affects approximately 2.5% of children and 8% of adolescents. Escitalopram is the S-enantiomer of citalopram.NCT00107120·Sacramento, California and 27 others

RecruitingLong-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)This study will evaluate the long-term safety and tolerability of NBI-1065845 as an adjunctive treatment in participants with MDD.NCT06966401·Huntsville, Alabama and 105 others

CompletedOpen-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major DepressionThe purposes of this study are to determine: The safety of duloxetine and any side effects that might be associated with it.NCT00042562·Carlsbad, California and 22 others

CompletedA Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive DisorderThe purpose of this study is to evaluate how well JNJ-89495120 works (anti-depressant effects) and how well it is tolerated as compared to placebo on reducing the symptoms of…NCT06785012·Huntsville, Alabama and 43 others

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) in Adult Outpatients With Major Depressive Disorder (MDD)A multicenter, 8-week study to evaluate the efficacy of 2 doses (50 and 100 mg/day) of desvenlafaxine succinate sustained-release (DVS SR) versus placebo in adult outpatients with…NCT01432457·Phoenix, Arizona and 60 others

CompletedA Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO StudyThe clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy.NCT04103892·Bentonville, Arkansas and 45 others

CompletedA Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive DisorderThe purpose of this study is to assess the effect and safety of AZD6765 in patients with major depressive disorder who exhibit inadequate response to antidepressants.NCT01482221·Chino, California and 43 others

RecruitingPrecision Depression Adalimumab TrialThe goal of this clinical trial is to learn if the anti-inflammatory medication adalimumab improves depressive symptoms in adults with Major Depressive Disorder (MDD) who are…NCT07845604·Philadelphia, Pennsylvania

CompletedA Study of 6(S)-5-MTHF Among Serotonin Reuptake Inhibitor(SSRI)-Resistant Outpatients With Major Depressive Disorder (MDD)The purpose of the study is to test whether oral 6(S)-5-MTHF (Deplin®) is safe and effective in relieving depression when it is added to standard kinds of antidepressants called…NCT00321152·San Diego, California and 10 others

CompletedEfficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and DepressionThe primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness…NCT00518986·Jasper, Alabama and 61 others

CompletedAccelerated TMS to a Novel Brain Target in MDD and PTSDThis is a Clinical Trial designed to evaluate novel transcranial magnetic stimulation (TMS) methods for treating depression/PTSD.NCT03114891·Philadelphia, Pennsylvania

CompletedA Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) TreatmentThe purpose of this study is to assess if LY2216684 (flexible dose of 12 to 18 milligrams \[mg\] or fixed dose of 6 mg once daily) is superior to placebo once daily in the…NCT01187407·Birmingham, Alabama and 53 others

RecruitingA Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive DisorderThe goal of this clinical trial is to learn if zelquistinel works to treat depression in adults. It will also learn about the safety of zelquistinel.NCT07115329·Phoenix, Arizona and 31 others

CompletedSafety and Efficacy of Cariprazine As Adjunctive Therapy In Major Depressive DisorderThis is an outpatient study to evaluate the safety, and efficacy of RGH-188 as an add-on therapy to standard antidepressants in patients who did not respond to previous…NCT00854100·Phoenix, Arizona and 40 others

CompletedA Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for SuicideThe purpose of this study is to evaluate the efficacy of intranasal esketamine 84 milligram (mg) compared with intranasal placebo along with standard care treatment, in reducing…NCT02133001·Birmingham, Alabama and 13 others

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