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Clareo Health | Melanoma Clinical Trials in Philadelphia | 224 Studies

Clinical Trials MelanomaPhiladelphia

Melanoma Clinical Trials in Philadelphia

Find 224 clinical trials for melanoma near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 224 trials

CompletedVaccine Therapy With or Without Cyclophosphamide in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV MelanomaRATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells.NCT00118274·Philadelphia, Pennsylvania and 2 others CompletedTretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus SyndromeRATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer.NCT00003601·Philadelphia, Pennsylvania CompletedMinimally Invasive Groin Dissection for MelanomaThe purpose of this this study is to determine if a structured educational training program is successful in teaching surgeons a new operative technique.NCT01500304·Scottsdale, Arizona and 10 others

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Data from ClinicalTrials.govTerms

CompletedA Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and…NCT03517488·Los Angeles, California and 16 others

Active not recruitingIDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal MelanomaThis is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be…NCT05987332·Scottsdale, Arizona and 67 others

CompletedMAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck CancersThis Phase 1 study is designed as a cell dose escalation trial in HLA-A\*02:01 and HLA-A\*02:06 subjects with MAGE-A10 positive urothelial, melanoma or head and neck tumors.NCT02989064·Boston, Massachusetts and 10 others

CompletedSafety Study of PLX4032 in Patients With Solid TumorsThe primary objective of this FIH study is to assess the safety and pharmacokinetics of PLX4032 in patients with solid tumors.NCT00405587·Los Angeles, California and 6 others

RecruitingA Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)This study is researching an experimental drug called fianlimab (also known as REGN3767), combined with another medication called cemiplimab (also known as REGN2810), called…NCT06246916·Chandler, Arizona and 111 others

CompletedSorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By SurgeryThis randomized phase II trial is studying how well giving sorafenib together with either temsirolimus or tipifarnib works in treating patients with stage IV melanoma that cannot…NCT00281957·Little Rock, Arkansas and 172 others

Active not recruitingPhase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer TherapiesThis is a multi-center, open-label Phase 0 Master Protocol designed to study the localized pharmacodynamics (PD) of anti-cancer therapies within the tumor microenvironment (TME)…NCT04541108·Shreveport, Louisiana and 8 others

RecruitingMC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced MelanomaIn this first-in human, phase I/IIa study, the safety and efficacy of \[212Pb\]VMT01, an alpha-particle emitting therapeutic agent targeted to melanocortin sub-type 1 receptor…NCT05655312·Orange, California and 12 others

CompletedA Study of SEA-CD40 Given With Other Drugs in CancersThis trial is being done to see if an experimental drug (SEA-CD40) works when it's given with other cancer drugs to treat some types of cancer.NCT04993677·Springdale, Arkansas and 28 others

CompletedDasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryRATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00700882·Little Rock, Arkansas and 152 others

CompletedPhase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01876 when given in combination with immune therapies in subjects with advanced or…NCT03126110·Los Angeles, California and 37 others

CompletedEvaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic MelanomaThe primary objectives of this study are: * To explore the antitumor activity of MEDI-522 ± DTIC in patients with metastatic melanoma.NCT00066196·Scottsdale, Arizona and 24 others

CompletedTrial of Dacarbazine With or Without Genasense in Advanced MelanomaThis study is being performed to prospectively determine whether dacarbazine plus Genasense is significantly better than dacarbazine plus placebo in chemotherapy-naive patients…NCT00518895·Mobile, Alabama and 76 others

Active not recruitingStudy Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With PembrolizumabThis Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to characterize the safety…NCT04130516·Los Angeles, California and 9 others

TerminatedA Phase 1 Study of [225Ac]-FPI-1434 InjectionThis is a first-in-human Phase 1/2, non-randomized, multi-centre, open-label clinical study designed to investigate safety, tolerability, PK, and preliminary anti-tumour activity…NCT03746431·Duarte, California and 12 others

Active not recruitingGEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid TumorsThe goal of this trial is to learn about the antibody GEN1042 when it is used alone and when it is used together with another antibody cancer drug, pembrolizumab (with or without…NCT04083599·Anchorage, Alaska and 75 others

CompletedCarboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase III trial studies carboplatin, paclitaxel, and sorafenib tosylate to see how well they work compared to carboplatin and paclitaxel in treating patients with…NCT00110019·Birmingham, Alabama and 218 others

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Other Conditions in Philadelphia

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma