Depression Clinical Trials

Showing 401-420 of 3,090 trials

Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury

NCT07224165

This is a feasibility trial of a digital mental health intervention aimed at adolescents (ages 14-18) with nonsuicidal self-injury and who are not currently engaged in mental health treatment. The study has two arms: a self-guided DMHI and an active control which will involve the delivery of non-interactive psychoeducational content via the same app interface. The primary goals of this project are to evaluate the feasibility of the intervention and trial procedures in preparation for a fully-powered randomized-controlled trial.

Nonsuicidal Self-injuryDepressionAnxiety

Northwestern University80 participantsStarted Jan 2026

RECRUITINGPhase 2/3

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

NCT05474846

To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this study, BLT, Methylphenidate and Melatonin will be compared to their placebos.

SleepFatigueAnxiety+2 more

M.D. Anderson Cancer Center188 participantsStarted Nov 2022

Houston, Texas, United States

Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

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