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Clareo Health | Depression Clinical Trials | 3,203 Studies Recruiting

Clinical TrialsDepression

Depression Clinical Trials

Browse 3,203 clinical trials for depression. Find studies that match your criteria and connect with research centers.

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Showing 1961-1980 of 3,203 trials

CompletedTreating Refractory Major Depressive Disorder With Repetitive Transcranial Magnetic StimulationStudies exploring the efficacy of repetitive transcranial magnetic stimulation (rTMS) as a treatment for refractory major depressive disorder (MDD) have shown significant promise.NCT00305045·Toronto, Ontario CompletedClinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive DisorderThis is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the…NCT04985942·Phoenix, Arizona and 53 others

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Data from ClinicalTrials.govTerms

CompletedN-methylglycine (Sarcosine) Treatment for DepressionMajor depressive disorder is a complex disease and most currently available antidepressants aiming at monoamine neurotransmission exhibit limited efficacy and cognitive effects.NCT00977353·Taichung

UnknownDBS in Treatment Resistant Major DepressionThis study aims at assessing efficacy and safety of DBS for treatment of patients suffering from resistant major depression, by means of a random, controlled and crossed study.NCT01268137·Barcelona

CompletedSafety, Tolerability and Pharmacokinetics Study of LY03005The purpose of this study is to evaluate the safety and tolerability of escalating single oral doses of LY03005 in healthy subjects and to characterize the pharmacokinetics (PK)…NCT02055300·Cincinnati, Ohio

CompletedMagnetic Resonance Imaging Study of Geriatric DepressionThe purpose of this study was to use Magnetic Resonance Images to further our understanding of predictors and markers of treatment response and non-response in geriatric…NCT00245557·Belmont, Massachusetts

RecruitingCannabidiol Oil for Treatment-Resistant Major DepressionMajor depressive disorder is one of the leading causes of disability worldwide, and a substantial proportion of patients do not achieve adequate improvement with conventional…NCT07696871·Tubarão, Santa Catarina

Active not recruitingA Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Major Depressive Disorder - EmergeNCT06941844·Little Rock, Arkansas and 21 others

CompletedSafety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive DisorderThis study will evaluate the long-term safety and tolerability of escitalopram (Lexapro) in children 7 to 11 years of age with major depressive disorder (MDD).NCT01198795·Dothan, Alabama and 15 others

CompletedTreatment of Patients With Major Depressive Disorder With MK0869 (0869-063)A clinical study to determine the efficacy and safety of MK0869 in the treatment of depression.NCT00034944

WithdrawnExpanding and Testing VA Collaborative Care Models for DepressionBased on the published evidence, collaborative care for depression is both necessary and sufficient for improving care and outcomes for depressed patients in primary care settings.NCT00119028·Long Beach, California and 5 others

Active not recruitingPhysical Activity-based Intervention in Depressed Patients: Clinical, Neurophysiological, Epigenetic and Metabolic CorrelatesThe goal of this clinical trial is to investigate the effect of a structured physical activity (PA) program on depressive symptomatology in adults with a diagnosis of major…NCT06989944·Brescia and 3 others

RecruitingA Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive DisorderThis study evaluates the safety and efficacy of brenipatide when administered with standard of care (SoC) compared to placebo plus SoC in delaying the return of major depressive…NCT07775300·Birmingham, Alabama and 168 others

CompletedA Comparison of Cognitive and Dynamic Therapy for Depression in Community SettingsThe goal of this study is to compare supportive-expressive therapy, a type of psychodynamic psychotherapy, with cognitive therapy for the treatment of depression in community…NCT01207271·Philadelphia, Pennsylvania

UnknownGlutamate Emotion Memory StudyClinical depression often includes a pessimistic view of things which have happened in the past and an impairment in the ability to experience pleasure or looking forward to…NCT05809609·Oxford

Active not recruitingKetamine Associated ACC GABA and Glutamate Change and Depression Remission:This is a feasibility study and the goal of this project is to evaluate whether peak ACC GABA and glutamate, quantified as a CSF-corrected absolute concentration percent change…NCT03573349·Rochester, Minnesota

CompletedEfficacy Study of Deep Brain Stimulation in Patients With Treatment Resistant Major DepressionThe primary objective of this multicenter, randomized, sham-controlled, double blind (patient and observer blinded) clinical trial is to assess the antidepressant effect of Deep…NCT03653858·Grenoble and 1 other

CompletedDepression, Epinephrine, and Platelet FunctionMen and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and…NCT00166114·Atlanta, Georgia

RecruitingPositive Processes and Transition to Health (PATH)The R33 will be a randomized controlled trial to replicate changes in the targets (unproductive processing, avoidance, reward deficits) from the R61 phase in a larger sample of…NCT06093906·Newark, Delaware and 2 others

UnknownPatient Stratification and Treatment Response Prediction in Neuropharmacotherapy Using Hybrid Positron Emmission Tomography/Magnetic Resconance Imaging (PET/MR)Selective serotonin reuptake inhibitors (SSRIs) raise serotonin (5-HT) in the synaptic cleft and are the current first line of pharmacological antidepressive treatment.NCT02711215·Vienna

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