Depression Clinical Trials

Showing 2021-2040 of 3,090 trials

Brain Aging and Treatment Response in Geriatric Depression

NCT01902004

The proposed project will evaluate the role of neuroimaging biomarkers of brain aging (i.e., neurodegenerative and vascular brain changes) and mild cognitive impairment in the patterns of treatment response to memantine combined with escitalopram compared to escitalopram and placebo.

Mild Cognitive Impairment (MCI)Depression

University of California, Los Angeles115 participantsStarted Oct 2013

Los Angeles, California, United States

COMPLETEDNA

Comparing Differing Financial Incentive Structures for Increasing Antidepressant Adherence Among Adults

NCT03441399

The investigators will test using financial incentives by leveraging decision-making biases to improve adherence to antidepressants among adults newly prescribed antidepressants. This study will compare the effects of usual care, increasing financial incentives, and decreasing financial incentives on daily antidepressant medication adherence and depression symptom control of non-elderly adults with Major Depressive Disorder.

Depression

University of Pennsylvania120 participantsStarted Mar 2018

Philadelphia, Pennsylvania, United States

COMPLETEDNA

Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for Depression

NCT02057042

The investigators will conduct a randomized clinical trial of Peer-Supported cCBT versus enhanced usual care (EUC) for 330 patients with new episodes of depression in primary care at three VA sites and their associated Community-Based Outpatient Clinics (CBOCs).

Depression

VA Office of Research and Development330 participantsStarted Jun 2015

Ann Arbor, Michigan, United States • Battle Creek, Michigan, United States • Detroit, Michigan, United States

Brain Aging and Treatment Response in Geriatric Depression

Comparing Differing Financial Incentive Structures for Increasing Antidepressant Adherence Among Adults

Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for Depression

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