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Clareo Health | Depression Clinical Trials in Houston | 165 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 165 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 121-140 of 165 trials

CompletedThe MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)The MOOD study will evaluate the safety and efficacy of a noninvasive, self-administered external Combined Occipital and Trigeminal Neurostimulation (eCOT-NS) treatment for Major…NCT04279522·La Jolla, California and 12 others CompletedXEN1101 for Major Depressive DisorderThis project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the…NCT04827901·New York, New York and 1 other CompletedA Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for SuicideThe purpose of this study is to evaluate the efficacy of intranasal esketamine 84 milligram (mg) compared with intranasal placebo along with standard care treatment, in reducing…NCT02133001·Birmingham, Alabama and 13 others

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Data from ClinicalTrials.govTerms

CompletedA Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of SuicideThe purpose of the study is to evaluate the efficacy, safety, and tolerability of SLS-002 (intranasal racemic ketamine) in addition to standard of care on symptoms of Major…NCT04669665·Orange, California and 20 others

CompletedA Trial of AXS-05 in Patients With Major Depressive DisorderA Phase 3, randomized, double-blind, placebo-controlled, multicenter trial of AXS-05 in patients with major depressive disorder (MDD).NCT04019704·Phoenix, Arizona and 42 others

CompletedSafety and Efficacy of Levomilnacipran ER in Adolescent Participants With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy, safety, and tolerability of levomilnacipran ER relative to placebo in adolescent outpatients (12-17 years) with Major…NCT02431806·Dothan, Alabama and 48 others

Active not recruitingSmoking Cessation for Depressed SmokersObjectives: Primary Aim: To conduct a preliminary randomized trial in smokers with current recurrent major depressive disorder (MDD), current MDD with a single episode of 2…NCT00494728·Houston, Texas

CompletedALTO-100 in MDD and/or PTSDThe goal of this study is to collect biologically based data for defining predictors and correlates of the effects of ALTO-100.NCT05117632·Tempe, Arizona and 22 others

CompletedBrexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant TreatmentTo evaluate the long-term efficacy and safety of brexpiprazole as an adjunctive treatment to an antidepressant treatment (ADT) for adult patients with Major Depressive Disorder…NCT01838681·Little Rock, Arkansas and 106 others

RecruitingZelquistinel or Placebo for the Reduction of Symptoms of Major Depressive DisorderThe goal of this clinical trial is to learn if zelquistinel works to treat depression in adults. It will also learn about the safety of zelquistinel.NCT06547489·Birmingham, Alabama and 33 others

CompletedAn Efficacy and Safety Study of Sirukumab in Participants With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy of sirukumab as adjunctive treatment to antidepressant therapy (monoaminergic antidepressant) where sirukumab (administered…NCT02473289·Birmingham, Alabama and 45 others

TerminatedA Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With AticaprantThe purpose of this study is to evaluate how well aticaprant works as compared with placebo when given along with an antidepressant therapy in improving the depressive symptoms in…NCT06514742·Huntsville, Alabama and 83 others

CompletedLong-Term Safety Of DVS-233 SR In Patients With Major Depressive DisorderThe study evaluated the long-term safety of Desvenlafaxine Succinate (DVS) Slow Release (SR) during open-label treatment in adult outpatients who had a primary diagnosis of major…NCT01309542·Birmingham, Alabama and 116 others

RecruitingSelf Neuro-modulation Therapy for Major Depressive Disorder (MDD) With AnhedoniaThe purpose of this research is to learn more about a new treatment for individuals with Major Depressive Disorder (MDD) with heightened symptoms of anhedonia (i.e. loss of…NCT06982820·Providence, Rhode Island and 2 others

RecruitingStudy to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression.NCT06786624·Little Rock, Arkansas and 17 others

CompletedEfficacy and Safety Study of BHV-7000 Monotherapy in Major DepressionThe purpose of this study is to determine the efficacy and safety of BHV-7000 in participants with Major Depressive Disorder (MDD)NCT06419608·Phoenix, Arizona and 61 others

CompletedMechanistic Evaluation of Response in TRD (MERIT)To evaluate the relapse prevention of AXS-05 relative to placebo in subjects with treatment resistant depression (TRD).NCT04608396·Little Rock, Arkansas and 19 others

CompletedTo Evaluate the Effects of NMRA-335140 on Symptoms of Major Depression in Participants With Bipolar II Disorder.This is a randomized, double-blind, placebo-controlled pilot study aiming to evaluate the effects of NMRA-335140 on symptoms of major depression in adults with Bipolar (BP) II…NCT06429722·Phoenix, Arizona and 20 others

TerminatedA Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an…NCT04855747·Homewood, Alabama and 69 others

RecruitingACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant ResponseThe goal of this clinical trial is to learn if ACP-211 can help treat adults with major depressive disorder (MDD) who have not improved with antidepressant therapy (ADT)…NCT07284667·Birmingham, Alabama and 25 others

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