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Clareo Health | Depression Clinical Trials in Houston | 165 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 165 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 101-120 of 165 trials

CompletedA Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With SeltorexantThe purpose of this study is to assess the efficacy of seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in…NCT04533529·Anaheim, California and 121 others

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Data from ClinicalTrials.govTerms

CompletedSafety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive DisorderAn outpatient study to evaluate the safety and efficacy of cariprazine as adjunct to antidepressant therapy (ADT) in participants with major depressive disorder (MDD) who have an…NCT01469377·Garden Grove, California and 71 others

RecruitingPhase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia SymptomsThe purpose of this study is to know how well seltorexant works, and also to evaluate safety and maintenance effect of seltorexant compared with placebo as an adjunctive therapy…NCT06559306·Birmingham, Alabama and 204 others

CompletedStudy of a Repetitive Transcranial Magnetic Stimulation (rTMS) Device for the Treatment of Major Depressive DisorderThis trial will test the safety and efficacy of a rTMS device for the treatment of major depressive disorder (MDD). It is hypothesized that rTMS will have an antidepressant effect.NCT00104611·Poway, California and 12 others

CompletedBrexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work EnvironmentTo investigate the efficacy and safety of flexibly dosed adjunctive brexpiprazole treatment in active adults with MDD, 18 to 35 years old, who are experiencing an inadequate…NCT02013609·Cerritos, California and 23 others

CompletedComparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRDThis is a multi-site, randomized, open-label, effectiveness trial comparing three treatment arms for Major Depressive Disorder (MDD) patients with TRD who are currently on…NCT02977299·Birmingham, Alabama and 12 others

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Peri- And Postmenopausal Women With Major Depressive Disorder (DVS 3364)A multicenter, 10-week study to evaluate the efficacy and safety of 50 mg of desvenlafaxine succinate sustained-release formulation (DVS SR) versus placebo in the treatment of…NCT01121484·Birmingham, Alabama and 43 others

CompletedEscitalopram in Adult Patients With Major Depressive DisorderThis is a short-term study to evaluate the efficacy, safety, and tolerability of escitalopram in adult patients (18 to 65 years of age) with moderate to severe depression.NCT00668525·Phoenix, Arizona and 44 others

CompletedA Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive DisorderDemonstrate ability of SEP-363856 to be superior to placebo as an adjunctive therapy to ADT in change from baseline in depressive symptoms (MADRS \& CGI-S) in MDD patients who had…NCT05593029·Birmingham, Alabama and 76 others

RecruitingLong-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)This study will evaluate the long-term safety and tolerability of NBI-1065845 as an adjunctive treatment in participants with MDD.NCT06966401·Huntsville, Alabama and 105 others

RecruitingA Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive DisorderMajor depressive disorder (MDD; depression) is a mood disorder that causes a continued feeling of sadness and loss of interest.NCT07276997·Dothan, Alabama and 32 others

CompletedOpen-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major DepressionThe purposes of this study are to determine: The safety of duloxetine and any side effects that might be associated with it.NCT00042562·Carlsbad, California and 22 others

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) in Adult Outpatients With Major Depressive Disorder (MDD)A multicenter, 8-week study to evaluate the efficacy of 2 doses (50 and 100 mg/day) of desvenlafaxine succinate sustained-release (DVS SR) versus placebo in adult outpatients with…NCT01432457·Phoenix, Arizona and 60 others

CompletedA Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO StudyThe clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy.NCT04103892·Bentonville, Arkansas and 45 others

CompletedA Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive DisorderThis study evaluates the efficacy, safety and tolerability of levomilnacipran extended-release (ER) compared with placebo in the prevention of depression relapse in major…NCT02288325·Birmingham, Alabama and 46 others

CompletedA Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive DisorderThe purpose of this study is to assess the effect and safety of AZD6765 in patients with major depressive disorder who exhibit inadequate response to antidepressants.NCT01482221·Chino, California and 43 others

CompletedDouble-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)This study is looking at the efficacy, durability, safety, and tolerability of multiple single doses of Ketamine vs. active placebo for treating patients with treatment resistant…NCT01920555·Palo Alto, California and 5 others

CompletedSafety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22)The purpose of this study is to evaluate the efficacy, safety, and tolerability of vilazodone compared with placebo in pediatric outpatients (7-17 years of age) with major…NCT02372799·Birmingham, Alabama and 59 others

CompletedEfficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and DepressionThe primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness…NCT00518986·Jasper, Alabama and 61 others

CompletedA Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) TreatmentThe purpose of this study is to assess if LY2216684 (flexible dose of 12 to 18 milligrams \[mg\] or fixed dose of 6 mg once daily) is superior to placebo once daily in the…NCT01187407·Birmingham, Alabama and 53 others

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