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Clareo Health | Depression Clinical Trials in Houston | 165 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 165 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 165 trials

RecruitingTreatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation…NCT06423430·Birmingham, Alabama and 24 others RecruitingA Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderThe purpose of this study is to evaluate how well JNJ-54135419 works (efficacy) in addition to comprehensive standard of care (SoC) in rapidly reducing the symptoms of major…NCT07227454·Birmingham, Alabama and 43 others

Depression Trials in Other Cities

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Data from ClinicalTrials.govTerms

RecruitingClinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using SolriamfetolCLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter…NCT07484217·Tucson, Arizona and 39 others

RecruitingA Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderThe purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD.NCT06793397·Birmingham, Alabama and 78 others

CompletedOpen-Label Safety Study of AXS-05 in Subjects With DepressionAn open-label, long-term, safety study of AXS-05 in patients with major depressive disorder (MDD), including treatment resistant depression.NCT04039022·Phoenix, Arizona and 50 others

CompletedNeuroStar TMS Therapy System: Utilization and OutcomesThe major objective of this observational study is to describe clinical outcomes of patients receiving treatment with the NeuroStar TMS Therapy system in routine clinical practice.NCT01114477·Phoenix, Arizona and 43 others

CompletedEfficacy and Safety of Vortioxetine (Lu AA21004) in Treating Adults With Major Depressive DisorderThe purpose of this study is to determine the efficacy and safety of once daily vortioxetine (Lu AA21004) in adults with major depressive disorder.NCT00672958·Birmingham, Alabama and 32 others

CompletedStudy to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)To assess the efficacy of pimavanserin compared to placebo when given adjunctively to a selective serotonin reuptake inhibitor (SSRI)/serotonin-norepinephrine reuptake inhibitor…NCT03018340·Birmingham, Alabama and 35 others

CompletedA Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)This study will evaluate the efficacy, safety, and tolerability of two doses of rapastinel, 225 milligrams (mg) and 450 mg, compared to placebo adjunctive to antidepressant…NCT02943564·Birmingham, Alabama and 65 others

Active not recruitingDBS of the Lateral Habenula in Treatment-Resistant DepressionThis research study will investigate the safety, tolerability, and benefit of bilateral deep brain stimulation (DBS) to the lateral habenula in subjects with treatment-resistant…NCT01798407·Houston, Texas

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal WomenDesvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI).NCT00369343·Birmingham, Alabama and 36 others

TerminatedA Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic FeaturesApproximately 450 patients will be randomized to receive mifepristone or placebo for 7 days followed by antidepressant.NCT00637494·Little Rock, Arkansas and 41 others

CompletedStudy of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive DyskinesiaThis study will evaluate the effectiveness of valbenazine on patient- and clinician-reported outcomes assessing health-related quality of life, functioning, and treatment effect…NCT05859698·Bryant, Arkansas and 17 others

TerminatedA Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD)The purpose of this study is to assess the long-term safety and tolerability of aticaprant administered as adjunctive therapy to a current antidepressant (selective serotonin…NCT05518149·Birmingham, Alabama and 233 others

SuspendedPramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIVA phase II, randomized, open-label, two-arm clinical trial evaluating the safety and efficacy of pramipexole extended release (ER) versus escitalopram for the treatment of major…NCT06705478·Birmingham, Alabama and 40 others

RecruitingStudy of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive DisorderThis is a multicenter, randomized, double-blind, placebo-controlled parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the…NCT05850689·Huntsville, Alabama and 68 others

CompletedAn 8 Week Depression Study In Adults Diagnosed With Major Depressive DisorderA Placebo Controlled Study Evaluating Efficacy, Safety and Tolerability of Radafaxine in Patients with Major Depressive Disorder (MDD)NCT00057239·Little Rock, Arkansas and 28 others

CompletedPivotal Trial (D02) of Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depression (TRD)To confirm the safety and efficacy of the NCP System in treating patients in a nmajor depressive episode.NCT00533832·Houston, Texas

CompletedGoal Achievement After a Change to Vortioxetine in Adults With Major Depressive DisorderThe purpose of this study is to determine the effectiveness of treatment with vortioxetine on participant goal achievement after a change in antidepressant medication for the…NCT02972632·Costa Mesa, California and 24 others

CompletedDepression Study In Elderly PatientsMajor Depressive Disorder (MDD) Study in Elderly OutpatientsNCT00067444·Little Rock, Arkansas and 45 others

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