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Clinical Trials Brain CancerBoston

Brain Cancer Clinical Trials in Boston

Find 158 clinical trials for brain cancer near Boston, Massachusetts. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 158 trials

Active not recruitingPediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGIndoximod was developed to inhibit the IDO (indoleamine 2,3-dioxygenase) enzymatic pathway, which is important in the natural regulation of immune responses.NCT04049669·Augusta, Georgia and 4 others CompletedA Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent GlioblastomaThe primary objective of this study is to evaluate the safety, efficacy and clinical activity of Pamiparib in combination with radiation therapy (RT) and/or temozolomide (TMZ) in…NCT03150862·Tucson, Arizona and 21 others

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Data from ClinicalTrials.govTerms

TerminatedCelecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RTRATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.NCT00068770·Tampa, Florida and 6 others

CompletedVEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to TemozolomideThis phase II trial is studying how well VEGF Trap works in treating patients with recurrent malignant or anaplastic gliomas that did not respond to temozolomide.NCT00369590·Los Angeles, California and 6 others

RecruitingAPL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsTo assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET…NCT03175224·Los Angeles, California and 34 others

CompletedDose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV GliomasIn this study an investigational replication-defective, recombinant adenovirus expressing the interferon-beta gene (BG00001) will be directly injected into tumors, in patients…NCT00031083·Birmingham, Alabama and 4 others

CompletedO(6)-Benzylguanine in Treating Patients With Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002971·Los Angeles, California and 8 others

RecruitingSafety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP LossThis is a first in human study of TNG456 alone and in combination with abemaciclib in patients with advanced or metastatic solid tumors known to have an MTAP loss.NCT06810544·Scottsdale, Arizona and 14 others

RecruitingImplantable Microdevice In Primary Brain TumorsThis pilot study will assess the safety and feasibility of using an implantable microdevice to measure local intratumor response to chemotherapy and other clinically relevant…NCT04135807·Boston, Massachusetts

CompletedErlotinib and Temsirolimus in Treating Patients With Recurrent Malignant GliomaErlotinib and temsirolimus and may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00112736·Los Angeles, California and 7 others

Active not recruitingVorinostat and Temozolomide in Treating Patients With Malignant GliomasThis phase I trial is studying the side effects and best dose of vorinostat when given together with temozolomide in treating patients with malignant gliomas.NCT00268385·Birmingham, Alabama and 16 others

RecruitingThe RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent GlioblastomaResection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site.NCT06273176·San Francisco, California and 7 others

CompletedChemotherapy in Treating Patients With Progressive or Recurrent Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012038·Birmingham, Alabama and 9 others

CompletedPazopanib in Treating Patients With Recurrent GlioblastomaThis phase II trial is studying the side effects and how well pazopanib works in treating patients with recurrent glioblastoma.NCT00459381·Los Angeles, California and 8 others

CompletedSurgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells.NCT00053183·Birmingham, Alabama and 9 others

TerminatedImatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurrent GliomaPhase I/II trial to estimate the maximum tolerated dose of imatinib mesylate in newly diagnosed brain stem gliomas and recurrent high grade gliomas and to assess the effectiveness…NCT00021229·San Francisco, California and 9 others

CompletedIrinotecan in Treating Patients With Recurrent Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003301·Birmingham, Alabama and 8 others

RecruitingStudy of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantThe goal of this study is to determine the efficacy of the 1) ribociclib and everolimus to treat pediatric and young adult patients newly diagnosed with a high-grade glioma (HGG)…NCT05843253·Aurora, Colorado and 19 others

CompletedAcupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic ChemotherapyRATIONALE: Acupressure wristbands may prevent or reduce nausea and caused by chemotherapy.NCT01346267·Long Beach, California and 24 others

CompletedTipifarnib in Treating Patients With Recurrent or Progressive Malignant GliomaRATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth.NCT00005859·Los Angeles, California and 10 others

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Clareo Health | Brain Cancer Clinical Trials in Boston | 158 Studies