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Clareo Health | Brain Cancer Clinical Trials in Boston | 158 Studies

Clinical Trials Brain CancerBoston

Brain Cancer Clinical Trials in Boston

Find 158 clinical trials for brain cancer near Boston, Massachusetts. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Boston

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 21-40 of 158 trials

CompletedRadiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as tamoxifen may make the tumor cells more sensitive to radiation therapy.NCT00006388·Birmingham, Alabama and 256 others

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Data from ClinicalTrials.govTerms

CompletedTemozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006024·Birmingham, Alabama and 234 others

CompletedAZD2171 in Treating Patients With Recurrent Glioblastoma MultiformeThis phase II trial is studying how well AZD2171 works in treating patients with recurrent glioblastoma multiforme.NCT00305656·Boston, Massachusetts

RecruitingThe SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)A greater extent of resection of the contrast-enhancing (CE) tumor part has been associated with improved outcomes in high-grade glioma patients.NCT06118723·San Francisco, California and 7 others

TerminatedEvaluating the Expression Levels of MicroRNA-10b in Patients With GliomasMicroRNAs (miRNA) are molecular biomarkers that post-transcriptionally control target genes. Deregulated miRNA expression has been observed in diverse cancers.NCT01849952·Boston, Massachusetts and 3 others

CompletedPhase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain TumourThis is a Phase I, open-label, multi-centre study designed to assess the safety and tolerability of Cediranib in combination with lomustine in patients with primary recurrent…NCT00503204·Boston, Massachusetts and 1 other

CompletedVaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain TumorRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00069940·Boston, Massachusetts

TerminatedTopotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid TumorsRATIONALE: Drugs used in chemotherapy, such as topotecan, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.NCT00112619·San Francisco, California and 10 others

CompletedA Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial TherapyThis is an event driven, adaptive design, a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 3 study of DSP-7888 Dosing Emulsion plus Bevacizumab…NCT03149003·Birmingham, Alabama and 60 others

RecruitingStudy of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIThe purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) better than using…NCT07326566·Birmingham, Alabama and 37 others

TerminatedMK0752 in Treating Young Patients With Recurrent or Refractory CNS CancerRATIONALE: MK0752 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00572182·San Francisco, California and 11 others

CompletedBusulfan in Treating Children and Adolescents With Refractory CNS CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006246·San Francisco, California and 7 others

RecruitingStudy of Olutasidenib and Temozolomide in HGGThe goal of this study is to determine the efficacy of the study drug olutasidenib to treat newly diagnosed pediatric and young adult patients with a high-grade glioma (HGG)…NCT06161974·Aurora, Colorado and 19 others

CompletedImmunotoxin Therapy in Treating Patients With Malignant GliomaRATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. This may be an effective treatment for malignant glioma.NCT00006268·Birmingham, Alabama and 10 others

CompletedSelinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade GliomasThis phase I trial studies the side effects and best dose of selinexor in treating younger patients with solid tumors or central nervous system (CNS) tumors that have come back…NCT02323880·Birmingham, Alabama and 22 others

CompletedTemozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00006025·Los Angeles, California and 8 others

Active not recruitingA Study of Berubicin in Adult Subjects With Recurrent Glioblastoma MultiformeThis is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study.NCT04762069·Little Rock, Arkansas and 47 others

CompletedRamucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma MultiformeRATIONALE: Monoclonal antibodies, such as ramucirumab and anti-PDGFR alpha monoclonal antibody IMC-3G3 (Olaratumab), can block tumor growth in different ways.NCT00895180·Birmingham, Alabama and 10 others

CompletedDasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or GliosarcomaThis phase II trial studies how well dasatinib works in treating patients with glioblastoma multiforme or gliosarcoma that has come back.NCT00423735·Mobile, Alabama and 187 others

CompletedEfaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00005855·Birmingham, Alabama and 8 others

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Other Conditions in Boston

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia