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Clareo Health | Colorectal Cancer Clinical Trials in Boston | 363 Studies

Clinical Trials Colorectal CancerBoston

Colorectal Cancer Clinical Trials in Boston

Find 363 clinical trials for colorectal cancer near Boston, Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 363 trials

CompletedStudy of TSR-033 With an Anti-programmed Cell Death-1 Receptor (PD-1) in Participants With Advanced Solid TumorsThis is a multicenter, open-label, first-in-human Phase 1 study evaluating the anti-lymphocyte activation gene-3 (LAG-3) antibody TSR-033 alone, in combination with the anti-PD-1…NCT03250832·Los Angeles, California and 11 others CompletedLower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal CancerThis randomized phase II trial studies how well lower-dose compared to standard dose regorafenib works in treating patients with colorectal cancer that has spread from the primary…NCT02368886·Phoenix, Arizona and 21 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

TerminatedStudy of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid TumorsThis is a Phase 1b/2 study to determine the recommended phase 2 dose (RP2D), safety and tolerability, pharmacokinetics (PK) and clinical activity of the glutaminase inhibitor…NCT03875313·Birmingham, Alabama and 8 others

CompletedCollection of Patient-Reported Symptoms and Performance Status Via the InternetThis pilot clinical trial studies how well using the internet to collect symptoms and the ability to carry out daily activities works in patients with enrolled on Cancer and…NCT00417040·Castro Valley, California and 94 others

Active not recruitingStudy of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationThis is a phase Ib/II open label study.NCT04699188·Atlanta, Georgia and 37 others

CompletedPhase 1 Study of MGD007 in Relapsed/Refractory Metastatic Colorectal CarcinomaThe primary goal of this Phase 1 study is to characterize the safety and tolerability of MGD007 and establish the maximum tolerated dose (MTD) and schedule of MGD007 administered…NCT02248805·New Haven, Connecticut and 7 others

TerminatedSequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal CancerThis randomized, open-label, multicenter study will evaluate the efficacy and safety of folinic acid (leucovorin), 5-fluorouracil (5-FU), oxaliplatin, and irinotecan (FOLFOXIRI) /…NCT01765582·Mobile, Alabama and 44 others

CompletedPhase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal CancerThis phase 1/2, multi-center, randomized, double-blind, placebo-controlled trial is designed to evaluate the efficacy and safety of AMG 655 when combined with mFOLFOX6 and…NCT00625651·Hot Springs, Arkansas and 60 others

TerminatedCombination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of cancer cells, either by killing the cells or…NCT00023868·Tucson, Arizona and 8 others

TerminatedStudy of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid TumorsThis study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene…NCT04383210·Birmingham, Alabama and 41 others

Active not recruitingAdd-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid TumoursAdd-Aspirin aims to assess whether regular aspirin use after standard curative therapy can prevent recurrence and improve survival in individuals with non-metastatic common…NCT02804815·Cork and 81 others

CompletedA Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal CancerThis research study is studying a drug as a possible treatment for p53 mutant metastatic colorectal cancer. The drug involved in this study is: -LamivudineNCT03144804·Boston, Massachusetts

CompletedOxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With SurgeryPURPOSE: This randomized phase III trial is studying giving oxaliplatin, leucovorin calcium, and fluorouracil together to compare how well they work when given together with or…NCT01150045·Mobile, Alabama and 841 others

RecruitingORACLE: Observation of ResiduAl Cancer With Liquid Biopsy EvaluationThe purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-stage solid tumors.NCT05059444·Birmingham, Alabama and 56 others

CompletedPhase 1 and 2 Study of PX-866 and CetuximabThe purpose of this Phase 1/2 open-label study is to determine the safety and efficacy of a cetuximab and PX-866 combination treatment.NCT01252628·Birmingham, Alabama and 39 others

TerminatedA First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid TumorsA first-in-human study using BDC-1001 as a single agent and in combination with nivolumab in HER2 expressing advanced malignanciesNCT04278144·Palo Alto, California and 20 others

CompletedA Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)The purpose of this study was to combine the PDR001 checkpoint inhibitor with each of four agents with immunomodulatory activity to identify the doses and schedule for combination…NCT02900664·Baltimore, Maryland and 22 others

Active not recruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid TumorsThis is a first-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of enzelkitug when administered as a single agent and in…NCT05581004·San Francisco, California and 31 others

CompletedMacrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal CancerThis randomized phase II trial studies how well macrogol 3350-based oral osmotic laxative (polyethylene glycol 3350) works in preventing cancer in patients at risk of colorectal…NCT00828984·Chicago, Illinois and 2 others

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