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Browse 1,172 clinical trials for anxiety. Find studies that match your criteria and connect with research centers.
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NCT05585749
In contemporary medicine, endoscopic procedures are often regarded as the gold standard for the diagnosis and treatment of gastrointestinal illnesses due to the essential role they play in these processes. Endoscopy is a minimally invasive procedure that allows direct visualization of the gastrointestinal tract using a flexible, camera-equipped instrument.However, due to their invasive nature, these methods pose certain challenges for both healthcare professionals and patients. In particular, the physical discomfort and pain experienced during the procedure can lead to a negative attitude toward the process in patients, which can indirectly affect the success of the procedure .Despite the fact that a number of studies have examined the impact of virtual reality applications on pain and anxiety during endoscopy, the conclusions remain inconsistent. Moreover, relatively few studies have assessed physiological signs of anxiety. Therefore, uncertainties remain regarding the generalizability of existing findings. The present study aimed to examine the effect of virtual reality application on pain, anxiety, and physiological parameters in patients undergoing endoscopy.
NCT06152913
A substantial part of children/adolescents with anxiety or obsessive-compulsive disorder (AD/OCD) do not profit substantially from first-choice treatment (i.e., cognitive behavioral therapy; CBT). For them, no evidence-based treatment is available. The aim of this project is to evaluate and optimize a newly-developed personalized, short, and intensive exposure-based intervention, 'HANDS-ON', for 'treatment non-responders'. Collaboration with children, parents and teachers, guided exposure in a child's natural environment, personalized treatment goals and meaning/motivation are central principles. Methods: A multiple baseline single-case experimental design is used (qualitative and quantitative). Participants are children/adolescents (10-18 years; N=12) with an AD/OCD diagnosis for whom standard CBT did not lead to sufficient improvement. Children and parents are asked to complete questionnaires before, during, and after the treatment. Children, parents, and school professionals will be asked to participate in qualitative interviews to evaluate their experiences with the HANDS-ON treatment program.