Clinical Trials in Boston

Showing 2661-2680 of 17,836 trials

A Study of NTX-1472 in Social Anxiety Disorder

NCT07323784

The primary goal of this Phase 2 clinical trial is to determine the effects of a novel V1a receptor antagonist (NTX-1472) in adults with Social Anxiety Disorder (SAD). The main questions this trial aims to answer are: * Is NTX-1472 safe and well tolerated in adults with SAD? * How effectively does NTX-1472 treat adults with SAD? Researchers will compare the effects of NTX-1472 with matching placebo (a look-alike capsule that contains no drug). Participants will: * Take NTX-1472 or matching placebo every day for 8 weeks * Visit the clinic 6 times over the course of 14 weeks for checkups and tests

Social Anxiety Disorder (SAD)

Newleos Therapeutics, Inc.100 participantsStarted Dec 2025

Pheonix, Arizona, United States • Encino, California, United States • Los Angeles, California, United States +8 more locations

SUSPENDED< 1 mile

Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE

NCT06310018

SONIC-PE is a multicenter, prospective, single-arm study of 10 patients with bilateral PE treated with ultrasound-facilitated, catheter-directed lower-dose fibrinolysis (total dose 8 mg tPA given as 2 mg/hour/catheter over 2 hours) followed by 50 patients (total dose 6 mg tPA given as 3 mg/hour/catheter given over 1 hour) with the EKOS+™ system to determine its impact on the change in RV-to-LV diameter, refined Modified Miller Score, and distal pulmonary vascular blood volume as well as to assess International Society on Thrombosis and Haemostasis (ISTH) major bleeding.

Pulmonary EmbolismRight Ventricular DysfunctionRight Ventricular Failure

Brigham and Women's Hospital60 participantsStarted Jan 2027

Boston, Massachusetts, United States

A Study of NTX-1472 in Social Anxiety Disorder

Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE

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Fecal Microbiota Transplant National Registry

Avo In R/R And Previously Untreated MCL

Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU)

Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application

Lipids, Inflammation, and CV Risk in RA

D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study

A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee

Recovery Protein Nutrition as a Countermeasure for Anabolic Resistance Following Sleep Loss

Precise Procedural and PCI Plan (P4)

Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

Study of GS-0151 in Participants With Rheumatoid Arthritis

A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC)