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Clareo Health | Melanoma Clinical Trials in Boston | 355 Studies

Clinical Trials MelanomaBoston

Melanoma Clinical Trials in Boston

Find 355 clinical trials for melanoma near Boston, Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Boston

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 21-40 of 355 trials

TerminatedAldesleukin and Pembrolizumab in Treating Patients With Stage III-IV MelanomaThis study will evaluate the safety and tolerability of IL-2 when given in combination with pembrolizumab to patients with advanced melanoma.NCT02748564·Maywood, Illinois and 4 others CompletedPhase I Clinical Trial of Tremelimumab Plus MEDI3617 in Patients With Unresectable Stage III or Stage IV MelanomaThis is an open label, phase I trial, testing the combination of Tremelimumab and MEDI3617 in patients with metastatic melanoma.NCT02141542·Boston, Massachusetts and 1 other TerminatedLeflunomide+Vemurafenib in V600 Mutant Met. MelanomaThis research study was intended to be a Phase I/II clinical trial, but the trial was terminated before the phase 1 portion was completed.NCT01611675·Boston, Massachusetts and 2 others

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Data from ClinicalTrials.govTerms

CompletedTrametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 MutationsThis phase II trial studies trametinib in treating patients with melanoma with v-Raf murine sarcoma viral oncogene homolog B (BRAF) non-V600 mutations that has spread to other…NCT02296112·Washington D.C., District of Columbia and 3 others

TerminatedS9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain MetastasesRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Stereotactic radiosurgery may kill more tumor cells.NCT00003911·Mobile, Alabama and 85 others

RecruitingTegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsThis phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or…NCT04851119·Birmingham, Alabama and 20 others

TerminatedITIL-168 in Advanced MelanomaDELTA-1 is a phase 2 clinical trial to evaluate the efficacy and safety of ITIL-168 in adult subjects with advanced melanoma who have previously been treated with a PD-1 inhibitor.NCT05050006·La Jolla, California and 21 others

CompletedSorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By SurgeryThis randomized phase II trial is studying how well giving sorafenib together with either temsirolimus or tipifarnib works in treating patients with stage IV melanoma that cannot…NCT00281957·Little Rock, Arkansas and 172 others

CompletedPembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid TumorsThis is an open-label, multicenter, Phase 1b platform study in subjects with advanced or metastatic solid tumors (Part 1a) and subjects with selected solid tumors (Part 1b and…NCT02646748·San Francisco, California and 16 others

TerminatedStudy to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for RecurrenceThe main purpose of this study is to compare the efficacy of bempegaldesleukin plus nivolumab versus nivolumab in patients with completely resected Stage IIIA/B/C/D, or Stage IV…NCT04410445·Scottsdale, Arizona and 211 others

TerminatedA Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid TumorsThis study will test the safety of a drug called PF-08046049/SGN-BB228 in participants with melanoma and other solid tumors that are hard to treat or have spread through the body.NCT05571839·Los Angeles, California and 36 others

RecruitingPhase 1/2 Study of Intravenous Injection of STX-003 in Advanced Solid Tumors as Monotherapy or in Combination With PembrolizumabProtocol Title: Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of STX-003…NCT07751042·Scottsdale, Arizona and 3 others

TerminatedPhase I Study of LXH254 in Patients With Advanced Solid Tumors Haboring MAPK Pathway AlterationsA Phase I Study of LXH254 in Patients With Advanced Solid Tumors That Harbor MAPK Pathway Alterations.NCT02607813·Boston, Massachusetts and 17 others

CompletedA Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3)This randomized, open-label study evaluated the efficacy, safety and tolerability of vemurafenib (RO5185426) as compared to dacarbazine in previously untreated patients with…NCT01006980·Birmingham, Alabama and 110 others

Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

Active not recruitingA Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid TumorsThis is a phase I, First-in-Human (FIH), open-label study to evaluate the safety, tolerability, pharmacokinetic (PK) profile, and preliminary efficacy of AB248 as monotherapy OR…NCT05653882·Duarte, California and 19 others

TerminatedRO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast CancerThis randomized phase I/II trial studies the side effects and the best dose of RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) when given together with…NCT01217411·Boston, Massachusetts and 1 other

RecruitingProject: Every Child for Younger Patients With CancerThis study gathers health information for the Project: Every Child for younger patients with cancer.NCT02402244·Birmingham, Alabama and 278 others

TerminatedStudy of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced MalignanciesA first-in-human study using BDC-3042 as a single agent and in combination with cemiplimab in patients with advanced malignanciesNCT06052852·Palo Alto, California and 5 others

TerminatedStudy to Evaluate the Safety, Tolerability, and Pharmacodynamics of Investigational Treatments in Combination With Standard of Care Immune Checkpoint Inhibitors in Participants With Advanced MelanomaThe purpose of this study is to determine the initial safety profile and initial antitumor activity of the combination treatments (immune checkpoint inhibitors \[nivolumab…NCT02723006·Tucson, Arizona and 13 others

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