Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hoffmann-La Roche
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
adults, \>/=18 years of age
metastatic melanoma, stage IIIC or IV (AJCC)
treatment-naïve (no prior systemic anticancer therapy)
positive for BRAF V600E mutation
measurable disease by RECIST criteria
negative pregnancy test and, for fertile men and women, effective contraception during treatment and for 6 months after completion
You may not be if
active central nervous system metastases
history of carcinomatous meningitis
severe cardiovascular disease within 6 months prior to study drug administration
previous malignancy within 5 years prior to study, except for basal or squamous cell carcinoma of the skin, melanoma in-situ, or carcinoma in-situ of the cervix
