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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 481 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 481 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 21-40 of 481 trials

CompletedA Clinical Efficacy Study Of An Oral Tyrosine Kinase Inhibitor Of VEGFR-2 Given In Combination With ChemotherapyThe purpose of this study is to determine whether CP-547,632, an oral VEGFR-2 tyrosine kinase inhibitor when given in combination with chemotherapy (carboplatin and paclitaxel) is…NCT00074854·Greenbrae, California and 19 others RecruitingA Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsPhase 1 dose escalation will determine the first cycle dose-limiting toxicities (DLTs), the maximum tolerated dose (MTD), the biologically effective dose and recommended Phase 2…NCT03093116·Duarte, California and 164 others

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Data from ClinicalTrials.govTerms

TerminatedA Study Of Oral GW572016 In Advanced Or Metastatic Non-Small Cell Lung CancerThis study was designed to evaluate and compare the efficacy of two dose schedules of an oral investigational drug for the treatment of advanced or metastatic non-small cell lung…NCT00073008·Jasper, Alabama and 30 others

Active not recruitingStudy BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 ExpressionThis clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of…NCT04180371·Encinitas, California and 27 others

TerminatedPembrolizumab and Itacitinib (INCB039110) for Non-Small Cell Lung CancerThis is a single center, single arm phase 2 study to establish the safety and efficacy of itacitinib (also known as INCB039110) administered in combination with pembrolizumab in…NCT03425006·Philadelphia, Pennsylvania

TerminatedTivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung CancerThis study is to determine if the combination regimen of tivantinib with erlotinib will improve overall survival relative to erlotinib alone in subjects with locally advanced or…NCT01244191·Tucson, Arizona and 303 others

CompletedPhase III of RRM1 & ERCC1 Directed Customized Chemotherapy for the Treatment of Patients With NSCLCThis is a clinical research study to evaluate if chemotherapy in the experimental arm (E) results in a better outcome compared to patients in the standard of care arm (C).NCT00499109·Lakeland, Florida and 8 others

TerminatedEvaluation of a New Anti-cancer Vaccine for Patients With Non-small Cell Lung Cancer, After Tumor Removal by SurgeryThe purpose of this clinical study is to assess the safety and immunogenicity of the immunotherapeutic product GSK 2302032A when given to Non-Small Cell Lung Cancer (NSCLC)…NCT01159964·Newark, Delaware and 36 others

TerminatedA Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced CancersMulti-center, open-label, first in human Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous…NCT04025216·Phoenix, Arizona and 9 others

CompletedABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung CancerThe drug ABR-217620 is a combination of two proteins, one that recognizes tumor cells and one that triggers an attack on the tumor cells by activating some white blood cells…NCT00132379·Philadelphia, Pennsylvania and 3 others

Active not recruitingEfficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)This trial will evaluate the safety and efficacy of pembrolizumab (MK-3475) in combination with platinum doublet neoadjuvant chemotherapy (NAC) before surgery \[neoadjuvant…NCT03425643·Gilbert, Arizona and 226 others

RecruitingA Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid TumorsThis is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2.NCT05150691·Cerritos, California and 101 others

CompletedEribulin Mesylate in Combination With Intermittent Erlotinib in Patients With Previously Treated, Advanced Non-Small Cell Lung CancerThis is a Phase 2, multicenter, randomized study of two different dose regimens of eribulin mesylate in combination with intermittent erlotinib in patients with previously…NCT01104155·Bessemer, Alabama and 63 others

Active not recruitingA Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)This is a Phase I/II, open-label, multi-center, multi-national, dose escalation, single agent study to assess the safety, tolerability, PK, PD, immunogenicity and anti-tumor…NCT02912949·Phoenix, Arizona and 63 others

RecruitingChemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE TrialThis phase III trial compares the effect of adding chemotherapy to immunotherapy (pembrolizumab) versus immunotherapy alone in treating patients with stage IIIB-IV lung cancer.NCT06096844·Fayetteville, Arkansas and 324 others

CompletedA Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced MalignanciesThis is a Phase 1, open-label, first-in-human (FIH) dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and…NCT02571036·Scottsdale, Arizona and 25 others

CompletedTPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced CancersThis is a phase 1/1b open label, multicenter dose escalation and dose expansion study to investigate the safety, tolerability and anti-tumor activity of TPST-1120, a small…NCT03829436·San Francisco, California and 10 others

CompletedSafety and Efficacy Study of Abraxane in Combination With Carboplatin to Treat Advanced NSCL Cancer in the ElderlyStudy comparing two regimens of nab-paclitaxel and carboplatin combination in elderly subjects (≥ 70 years old) with advanced NSCLCNCT02151149·Tucson, Arizona and 54 others

CompletedA Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)This study will investigate the utility of biomarker-based triage for study participants with advanced non-small cell lung cancer (NSCLC) without prior systemic therapy.NCT03516981·Tempe, Arizona and 80 others

CompletedTrastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung CancerRATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.NCT00003881·Scottsdale, Arizona and 70 others

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Other Conditions in Philadelphia

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma