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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 481 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 481 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 41-60 of 481 trials

UnknownCAR-macrophages for the Treatment of HER2 Overexpressing Solid TumorsPhase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.NCT04660929·Duarte, California and 6 others CompletedRadiation Therapy in Treating Patients With Non-small Cell Lung CancerRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00002577·Birmingham, Alabama and 241 others

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Data from ClinicalTrials.govTerms

RecruitingMOv19-BBz CAR T Cells in FRa+ CancersThis is a Phase I open-label clinical trial to assess the safety, feasibility, and preliminary efficacy of intrapleural administration of MOv19-BBz CAR T cells in patients with…NCT07116057·Philadelphia, Pennsylvania

Active not recruitingPhase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic AlterationsThis is a Phase III, randomized, open-label, multicenter, global study to compare the efficacy and safety of Datopotamab Deruxtecan (Dato-DXd) in combination with durvalumab and…NCT05687266·Phoenix, Arizona and 253 others

RecruitingSafety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung CancerThe first phase of this study was an open label, randomized pilot study. Enrollment for this phase is now complete.NCT03546829·Philadelphia, Pennsylvania

RecruitingRadiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung CancerThis study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination…NCT06686771·Phoenix, Arizona and 74 others

CompletedA Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumors (ARTISTRY-2)This study will characterize the safety and tolerability and identify the recommended Phase 2 dose (RP2D) of subcutaneous (SC) ALKS 4230 as monotherapy and in combination with…NCT03861793·Los Angeles, California and 47 others

TerminatedBempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid TumorsThis study is to assess the safety and tolerability, and to assess the preliminary clinical benefit of NKTR-214 when combined with pembrolizumab (KEYTRUDA®) with or without…NCT03138889·Fayetteville, Arkansas and 37 others

RecruitingA Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)HCC is a common cancer worldwide and a leading cause of cancer-related death.NCT06858813·Duarte, California and 21 others

CompletedCetuximab in Treating Patients With Recurrent or Stage IIIB or Stage IV Lung CancerRATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00103207·Aurora, Colorado and 156 others

CompletedSafety Study of XL765 (SAR245409) in Combination With Erlotinib in Adults With Solid TumorsThe purpose of this study is to evaluate the safety and tolerability of XL765 in combination with erlotinib (Tarceva®) in subjects with solid tumors.NCT00777699·Philadelphia, Pennsylvania

CompletedImproving Clinical Trial Awareness in NSCLC: Pilot Testing A Novel Healthcare IT Platform for Incorporating Education at the Point of CareThe objective of this study is to 1) evaluate the impact of a novel individualized care planning/ educational technology (the On Q Care Planning System or CPS) on oncology patient…NCT02558998·Philadelphia, Pennsylvania

TerminatedStudy to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) PatientsRociletinib is a novel, potent, small molecule irreversible tyrosine kinase inhibitor (TKI) that selectively targets mutant forms of the epidermal growth factor receptor (EGFR)…NCT01526928·Duarte, California and 48 others

CompletedRAV12 in Treating Patients With Metastatic or Recurrent AdenocarcinomaRATIONALE: Monoclonal antibodies, such as RAV12, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00101972·Santa Monica, California and 4 others

CompletedStudy of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)The primary objectives of the study are: * To compare the overall survival (OS) of cemiplimab versus standard-of-care platinum-based chemotherapies in the first-line treatment of…NCT03088540·Albury, New South Wales and 191 others

RecruitingA Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid TumorsThe goal of this clinical trial is to test CPO301, a type of drug called an antibody drug conjugate in adult patients with advanced or metastatic solid tumors.NCT05948865·Los Angeles, California and 13 others

CompletedA Study of a Personalized Cancer Vaccine Targeting Shared NeoantigensThe purpose of this study is to evaluate the dose, safety, immunogenicity and early clinical activity of GRT-C903 and GRT-R904, a neoantigen-based therapeutic cancer vaccine, in…NCT03953235·Phoenix, Arizona and 11 others

CompletedTrial of Consolidation Pembrolizumab After Concurrent Chemotherapy and Proton Reirradiation for Thoracic Recurrences of Non-Small Cell Lung CancerThe main purpose of this study is to assess the safety, tolerability and anti-tumor activity of the experimental study drug pembrolizumab (also known as Keytruda or MK-3475) in…NCT03087760·Philadelphia, Pennsylvania

RecruitingTocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based TherapyThis is a research study to evaluate the safety and effectiveness of tocilizumab in combination with atezolizumab to treat non-small cell lung cancer.NCT04691817·Philadelphia, Pennsylvania

CompletedCombination Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00043108·Philadelphia, Pennsylvania

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Other Conditions in Philadelphia

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma