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Clinical Trials Lung CancerBoston

Lung Cancer Clinical Trials in Boston

Find 649 clinical trials for lung cancer near Boston, Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 481-500 of 649 trials

Active not recruitingA Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)The study will evaluate the efficacy and safety of treatment with chemotherapy in combination with osimertinib compared to chemotherapy in combination with placebo in patients…NCT04765059·Silver Spring, Maryland and 39 others CompletedNivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung CancerThe purpose of part 1 of this study is to determine the objective response rate (ORR) in stage IV NSCLC subjects treated with nivolumab in combination with ipilimumab as first…NCT02659059·San Diego, California and 31 others

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Data from ClinicalTrials.govTerms

Active not recruitingOsimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase InhibitorThis phase I trial studies the safety, side effects and best dose of necitumumab when given together with osimertinib in treating patients with EGFR-mutant non-small cell lung…NCT02496663·Duarte, California and 14 others

CompletedAZD8186 First Time In Patient Ascending Dose StudyThis is a phase I, open-label, multicentre study of AZD8186 administered orally in patients with advanced castrate-resistant prostate cancer (CRPC), squamous non-small cell lung…NCT01884285·Boston, Massachusetts and 12 others

Active not recruitingTesting the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung CancerThis phase II trial compares cabozantinib alone and the combination of cabozantinib and nivolumab to standard chemotherapy in the treatment of patients with non-squamous non-small…NCT04310007·Birmingham, Alabama and 610 others

Active not recruitingOsimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung CancerThis research study is studying a combination of two drugs as a possible treatment for Non-Small Cell Lung Cancer (NSCLC) with an EGFR mutation.NCT03122717·Boston, Massachusetts and 1 other

RecruitingA Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid MalignanciesThis research study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer agentsNCT05123482·Duarte, California and 66 others

CompletedCombination Chemotherapy Compared With No Treatment Following Surgery in Treating Patients With Non-small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002823·Atlantis, Florida and 122 others

RecruitingIvonescimab Alone And With Carboplatin/Pemetrexed For NSCLCThe goal of this clinical trial is to assess the efficacy of ivonescimab monotherapy in patients with advanced non-small cell lung cancer harboring actionable genomic alterations…NCT07405190·Boston, Massachusetts and 2 others

RecruitingAMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsThe purpose of this first-in-human study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AMG 410 when…NCT07094113·Duarte, California and 38 others

CompletedPemetrexed Disodium and Bevacizumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from…NCT00268489·Anchorage, Alaska and 247 others

CompletedPhase 3 Study of Bavituximab Plus Docetaxel Versus Docetaxel Alone in Patients With Late-stage Non-squamous Non-small-cell Lung CancerThe primary purpose of this research study is to see whether adding bavituximab (an investigational drug) to the standard chemotherapy drug docetaxel, will improve the results of…NCT01999673·Huntsville, Alabama and 160 others

CompletedS0027: Vinorelbine Followed by Docetaxel in Treating Patients With Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00026156·Mobile, Alabama and 95 others

CompletedStudy of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)This is a study of the efficacy, pharmacokinetics, and safety of DS-1062a in participants with advanced or metastatic non-small cell lung cancer (NSCLC) with known actionable…NCT04484142·Phoenix, Arizona and 83 others

RecruitingFiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLCThe goal of this clinical study is to learn more about the study drug, TUB-040, including its safety, tolerability, pharmacokinetics, and preliminary efficacy, and to determine…NCT06303505·Birmingham, Alabama and 20 others

CompletedA Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung CancerA Phase 1-2 study of MM-121 in combination with standard therapy for non-small cell lung cancer (NSCLC).NCT00994123·Birmingham, Alabama and 37 others

CompletedPhase 1 Study of Intradermal LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1This is a Phase 1 multi-center study to evaluate the clinical safety and immune response of ID-LV305 when injected intradermally in patients with advanced cancer.NCT02122861·San Francisco, California and 6 others

CompletedSafety and Efficacy Study of Abraxane as Maintenance Treatment After Abraxane Plus Carboplatin in 1st Line Stage IIIB / IV Squamous Cell Non-small Cell Lung CancerMaintenance treatment of advanced stage squamous cell NSCLC.NCT02027428·Huntsville, Alabama and 118 others

TerminatedAZD2014 and Weekly Paclitaxel in Squamous NSCLCOpen--label, phase 2a, multi-centre, single-arm study to assess the efficacy and safety of AZD2014 and weekly paclitaxel in patients with squamous non-small cell lung cancer…NCT02403895·Boston, Massachusetts and 6 others

CompletedLymph Node Removal in Treating Patients With Stage I or Stage II Non-small Cell Lung CancerRATIONALE: Surgical removal of all lymph nodes in the chest may kill cancer cells that have spread from tumors in the lung.NCT00003831·Mobile, Alabama and 73 others

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