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Clareo Health | Lung Cancer Clinical Trials in Boston | 649 Studies

Clinical Trials Lung CancerBoston

Lung Cancer Clinical Trials in Boston

Find 649 clinical trials for lung cancer near Boston, Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Healthy volunteers too

Showing 501-520 of 649 trials

Active not recruitingComparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung CancerRATIONALE: Wedge resection or segmentectomy may be less invasive types of surgery than lobectomy for non-small cell lung cancer and may have fewer side effects and improve…NCT00499330·Birmingham, Alabama and 385 others

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Data from ClinicalTrials.govTerms

CompletedA Study of MGD013 in Patients With Unresectable or Metastatic NeoplasmsThe primary goal of this Phase 1 study is to characterize the safety and tolerability of tebotelimab and establish the maximum tolerated dose (MTD) of tebotelimab in advanced…NCT03219268·Gilbert, Arizona and 39 others

CompletedErlotinib Plus Tivantinib (ARQ 197) Versus Single Agent Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to evaluate progression-free survival among subjects with KRAS mutation positive Non-Small Cell Lung Cancer (NSCLC) treated with erlotinib plus…NCT01395758·Stanford, California and 12 others

CompletedPhase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor MalignanciesA phase 1/2, open-label, study to determine the safety and preliminary efficacy of APR-246 in combination with pembrolizumab in subjects with solid tumor malignancies.NCT04383938·Phoenix, Arizona and 7 others

CompletedA Study of Capmatinib (INC280) in NSCLC Patients With MET Exon 14 Alterations Who Have Received Prior MET InhibitorThis research study is studying capmatinib as a treatment for advanced non-small cell lung cancer with MET exon 14 skipping, where the participant has already received prior…NCT02750215·Boston, Massachusetts

CompletedA Study of Tislelizumab in Combination With Investigational Agents in Participants With Non-Small Cell Lung CancerThe purpose of this study is to assess the antitumor activity, safety, and tolerability of tislelizumab plus investigational agent(s) with or without chemotherapy.NCT05635708·Los Angeles, California and 60 others

RecruitingA Phase I Study of SIM0505 in Participants With Advanced Solid TumorsThis is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult Participants with…NCT06792552·Orlando, Florida and 16 others

RecruitingA Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) MutationThe main purpose of the trial is to assess whether the trial drug, KST-6051, is safe and tolerable when administered orally, alone or in combination with other anticancer agents…NCT07458347·Los Angeles, California and 8 others

CompletedAn Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung CancerThis is a phase II, open-label, multicenter, randomized study to evaluate the efficacy and safety of GSK1120212 compared with docetaxel in the second line setting for subjects…NCT01362296·Scottsdale, Arizona and 59 others

TerminatedA Study to Investigate LYL845 in Adults With Solid TumorsThis is an open-label, multi-center, dose-escalation study with expansion cohorts, designed to evaluate the safety and anti-tumor activity of LYL845, an epigenetically…NCT05573035·Sacramento, California and 17 others

CompletedStudy of Palbociclib in Combination With Binimetinib for Patients With Advanced KRAS Mutant Non-Small Cell Lung CancerThis trial is being conducted as a possible treatment for lung cancer with a specific change in the KRAS gene. The drugs involved in this study are: * Palbociclib * BinimetinibNCT03170206·Boston, Massachusetts

CompletedA Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced CancerThe purpose of this study is to find a recommended schedule and dose range for Emibetuzumab when given with ramucirumab that may be safely given to participants with cancer.NCT02082210·Boston, Massachusetts and 3 others

CompletedZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)The purpose of the run-in phase of this study is to determine the appropriate and tolerable dose of ZD6474 (200mg or 300mg) to be administered in combination with paclitaxel and…NCT00071188·Concord, California and 33 others

CompletedA Study of PDR001 in Combination With LCL161, Everolimus or PanobinostatThe purpose of this study was to combine the PDR001 checkpoint inhibitor with several agents with immunomodulatory activity to identify the doses and schedule for combination…NCT02890069·Santa Monica, California and 24 others

CompletedSafety and Effect of Pertuzumab in Patients With Advanced Non-Small Cell Lung Cancer, Which Has Progressed After Prior ChemotherapyThe purpose of this study is to determine if the study drug pertuzumab is effective in treating patients with advanced lung cancer that has recurred following prior chemotherapy.NCT00063154·Scottsdale, Arizona and 7 others

TerminatedEfficacy and Safety of Momelotinib Combined With Trametinib in Adults With Metastatic KRAS-mutated Non-Small Cell Lung Cancer (NSCLC) Who Have Failed Platinum-Based Chemotherapy Preceded by a Dose-finding Lead-in PhaseThis study is conducted in two phases.NCT02258607·Duarte, California and 4 others

CompletedA Neoadjuvant Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Versus Chemotherapy Alone in Early Stage Non-Small Cell Lung Cancer (NSCLC)The purpose of this neoadjuvant study is to compare nivolumab plus chemotherapy and chemotherapy alone in terms of safety and effectiveness, and to describe nivolumab plus…NCT02998528·Glendale, Arizona and 137 others

CompletedA Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or LymphomaThe purpose of this study is to evaluate the safety, pharmacokinetics (study of what the body does to a drug), and pharmacodynamics (study of what a drug does to the body) of…NCT01703481·Birmingham, Alabama and 36 others

CompletedBortezomib With or Without Docetaxel in Treating Patients With Relapsed or Refractory Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy such as docetaxel use different ways to stop tumor cells from dividing so they stop growing or die.NCT00064012·Birmingham, Alabama and 20 others

CompletedStudy of NOV-002 in Combination With Chemotherapy to Treat Lung CancerThe purpose of this clinical trial is to find out whether or not the combination of NOV-002 with chemotherapy (paclitaxel and carboplatin) is better at improving overall survival…NCT00347412·Muscle Shoals, Alabama and 74 others

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