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Clinical Trials Lung CancerBoston

Lung Cancer Clinical Trials in Boston

Find 649 clinical trials for lung cancer near Boston, Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 281-300 of 649 trials

RecruitingA Phase 1 Study of LNCB74 in Advanced Solid TumorsThis is an open-label, phase 1, dose escalation and dose expansion study to determine safety and tolerability, and to determine the maximum tolerated dose and / or recommended…NCT06774963·Newport Beach, California and 16 others CompletedA Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic TumorsThis is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pharmacokinetics of autogene…NCT03289962·Scottsdale, Arizona and 32 others

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Data from ClinicalTrials.govTerms

CompletedImmune Checkpoint Inhibitors and Atherosclerotic Plaque VolumeIn this study, investigators plan to test whether Immune Checkpoint Inhibitor (ICI) treatment leads to an accelerated progression of atherosclerosis in patients with lung cancer.NCT04430712·Boston, Massachusetts

CompletedS0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung CancerRATIONALE: Studying samples of blood and tissue from smokers (closed to entry as of 7/15/07) and non-smokers with cancer in the laboratory may help doctors learn more about…NCT00450281·Anchorage, Alaska and 404 others

CompletedA Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)This is an open-label, Phase 1, dose-escalation study to determine the maximum tolerated dose (MTD) and the recommended phase two dose (RPTD), and to assess the safety…NCT03234712·Springdale, Arkansas and 17 others

Active not recruitingStudy of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with…NCT04380636·Mobile, Alabama and 204 others

Active not recruitingGenetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery.NCT02194738·Birmingham, Alabama and 1659 others

TerminatedA Study of Alectinib in RET-rearranged Non-small Cell Lung Cancer or RET-mutated Thyroid CancerThis research trial is studying a drug called alectinib as a possible treatment for non-small cell lung cancer (NSCLC) with specific genetic alterations known as ALK or RET…NCT03131206·Irvine, California and 3 others

TerminatedProton Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung CancerStereotactic body radiation therapy (SBRT) is a special form of treatment which pinpoints high doses of radiation directly to cancer.NCT01525446·Boston, Massachusetts

CompletedSafety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)The administration of Anamorelin in patients with Stage III-IV non-small cell lung cancer-cachexia (NSCLC-C) is expected to increase appetite, lean body mass, weight gain, and…NCT01387269·Fullerton, California and 59 others

CompletedSafety and Efficacy of BKM120 in Patients With Metastatic Non-small Cell Lung CancerThe purpose of this two-stage phase II study is to assess the efficacy of BKM120, as measured by determining the progression free survival (PFS), in patients with pretreated…NCT01297491·Chandler, Arizona and 91 others

CompletedNeoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLCThis is a research study to test the effectiveness of nab-paclitaxel + carboplatin + MPDL3280A for treatment of non-small-cell lung carcinoma (NSCLC), which is a type of lung…NCT02716038·Boston, Massachusetts and 2 others

TerminatedStudy to Investigate DRP-104 in Adults With Advanced Solid TumorsThe purpose of this study is to characterize the safety, tolerability, pharmacokinetics, pharmaco-dynamics and preliminary anti-tumor activity of DRP-104 (sirpiglenastat)…NCT04471415·Scottsdale, Arizona and 21 others

CompletedChemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By SurgeryThis randomized phase III trial studies chemotherapy and bevacizumab to see how well they work compared to chemotherapy alone in treating patients with stage IB, stage II, or…NCT00324805·Anniston, Alabama and 1168 others

TerminatedA Study of the Effect of R1507 in Combination With Tarceva (Erlotinib) on Progression-Free Survival in Patients With Stage IIIb/IV Non-Small Cell Lung Cancer (NSCLC).This 4 arm study in patients with advanced Stage IIIb/IV non-small cell cancer (NSCLC) who failed at least one standard chemotherapy regimen will determine the proportion of…NCT00760929·Beverly Hills, California and 56 others

CompletedA Phase 1/2 Study of Anvumetostat in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid TumorsThe main aims of this study are to evaluate the safety and tolerability, and to determine the maximum tolerated dose (MTD) or the recommended combination dose of Anvumetostat in…NCT05975073·Duarte, California and 26 others

RecruitingPhase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid TumorsThis is a Phase 1, multicenter, open-label dose escalation study to determine the safety and tolerability of intratumoral (IT) injection of tolododekin alfa (ANK-101) in…NCT06171750·Bethesda, Maryland and 4 others

Active not recruitingA Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung CancerThis randomized, active-controlled, multicenter, open-label, Phase III study is designed to investigate the efficacy and safety of alectinib compared with platinum-based in the…NCT03456076·Chicago, Illinois and 113 others

Active not recruitingU3-1402 in Metastatic or Unresectable Non-Small Cell Lung CancerThis study was designed to evaluate safety and antitumor activity of HER3-DXd in two parts: Dose Escalation and Dose Expansion.NCT03260491·Duarte, California and 36 others

CompletedImproving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced CancerThe purpose of this study is to refine and pilot test educational material developed to educate and support patients receiving immunotherapy for advanced cancer.NCT04670445·Boston, Massachusetts

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