Cases:

Subjects with non-small cell lung cancer treated with Immune Checkpoint Inhibitors.

Available contrast enhanced CT scans of the chest both immediately pre-ICI (\< 1 month) and latest follow-up.

Controls:

Subjects with non-small cell lung cancer, age, cancer stage and cardiovascular risk factor matched to cases.

Available contrast enhanced CT scan of the chest at two time-points at a similar interval between scans as the cases.

Immune Checkpoint Inhibitors and Atherosclerotic Plaque Volume