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Clareo Health | Lung Cancer Clinical Trials in Boston | 649 Studies

Clinical Trials Lung CancerBoston

Lung Cancer Clinical Trials in Boston

Find 649 clinical trials for lung cancer near Boston, Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 261-280 of 649 trials

RecruitingNano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic CancerThis research study is being done to help determine the safety and efficacy of gadolinium based nanoparticle, Activation and Guidance of Irradiation X (AGuIX), used in conjunction…NCT04789486·Boston, Massachusetts and 1 other Approved for marketingExpanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) ActivationExpanded access for participants with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other…NCT03906331·Goodyear, Arizona and 63 others

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Data from ClinicalTrials.govTerms

RecruitingA Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsThis is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with…NCT05592626·Sacramento, California and 18 others

Active not recruitingFc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced CancerThis study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) profiles of a novel fragment…NCT03860272·Scottsdale, Arizona and 17 others

Active not recruitingStudy of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid TumorsThe goal of this interventional clinical trial is to learn about TNG260, a CoREST inhibitor, in combination with pembrolizumab in patients with advanced solid tumors with a known…NCT05887492·Santa Monica, California and 12 others

CompletedHealthy Directions After Lung Surgery PilotThe objective of this proposal is to test the feasibility and acceptability of a lifestyle risk reduction intervention for patients with lung cancer receiving surgical treatment.NCT02135211·Boston, Massachusetts and 1 other

RecruitingChemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE TrialThis phase III trial compares the effect of adding chemotherapy to immunotherapy (pembrolizumab) versus immunotherapy alone in treating patients with stage IIIB-IV lung cancer.NCT06096844·Fayetteville, Arkansas and 329 others

CompletedCisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung CancerThis randomized phase I/II trial studies the side effects and best dose of veliparib when given together with or without cisplatin and etoposide and to see how well they work in…NCT01642251·Loma Linda, California and 427 others

CompletedA Study Of Combined C- MET Inhibitor And PAN-HER Inhibitor (PF-02341066 And PF-00299804) In Patients With Non- Small Cell Lung CancerLung cancer tumors become resistant to the first generation epidermal growth factor receptor (EGFR) inhibitors erlotinib or gefitinib by changing and increasing the activity of…NCT01121575·Aurora, Colorado and 9 others

No longer availableExpanded Access For Lorlatinib For Patients With Non Small Cell Lung Cancer ALK Positive or ROS1 PositiveThis expanded access study has being designed following a demand from the FDA, given the increase in the number of request for single patient INDs for lorlatinibNCT03178071·Sedona, Arizona and 48 others

CompletedEarly Palliative Care in Advanced Lung and Gastrointestinal MalignanciesThe purpose of this study is to compare two types of care - standard oncology care and standard oncology care with early palliative care (started soon after diagnosis) to see…NCT01401907·Boston, Massachusetts

Active not recruitingFirst-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)This study is one single group of participants with non-small cell lung cancer (NSCLC) who have not been cured by other treatments.NCT03401385·Los Angeles, California and 17 others

Active not recruitingStudy of Oral MRT-2359 in Selected Cancer PatientsThis Phase 1/2, open-label, multicenter study is conducted in patients with previously treated selected solid tumors, including non-small cell lung cancer (NSCLC), small cell lung…NCT05546268·Scottsdale, Arizona and 16 others

CompletedHigh Dose Gefitinib for the Treatment of Carcinomatous Meningitis in Adult Patients With Non-Small Cell Lung Cancer and Known or Suspected EGFR MutationsThe primary purposes of this study are to find out if using high doses of the drug Gefitinib (Iressa) as a way to treat patients with non-small cell lung cancer that has spread to…NCT00372515·Boston, Massachusetts and 1 other

RecruitingPhase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal CancersThe purpose of this study is to evaluate the safety, tolerability, dosimetry and preliminary efficacy of \[177Lu\]Lu-NNS309 and the safety, dosimetry and imaging properties of…NCT06562192·Birmingham, Alabama and 28 others

CompletedSym015 (Anti-MET) in Patients With Advanced Solid Tumor MalignanciesThis is the first study to test Sym015 in humans.NCT02648724·Aurora, Colorado and 26 others

CompletedAmifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung CancerRATIONALE: Amifostine may be an effective treatment for the toxic side effects caused by radiation therapy and chemotherapy.NCT00003313·Birmingham, Alabama and 263 others

CompletedSRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (DRAGON)This was a multi-center, open-label, Phase 1, first-in-human (FIH), dose-escalation, and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK)…NCT04291079·Fullerton, California and 21 others

Active not recruitingImmune and Genomic Markers in ALK+ NSCLCThe purpose of this research study is to obtain and study clinical history, and tissue and saliva specimens if available from participants with Anaplastic Lymphoma Kinase-ALK+…NCT04881916·Boston, Massachusetts

CompletedA Personal Cancer Vaccine (NEO-PV-01) w/ Nivolumab for Patients With Melanoma, Lung Cancer or Bladder CancerThe purpose of this study is to evaluate if the treatment with NEO-PV-01 + adjuvant in combination with nivolumab is safe and useful for patients with certain types of cancer.NCT02897765·Duarte, California and 8 others

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