Hepatitis Clinical Trials

Showing 1501-1520 of 1,819 trials

A Study to Assess the Effectiveness, Safety, and Pharmacokinetics of TMC435 in Combination With Peginterferon Alfa-2a and Ribavirin in Hepatitis-C Infected Patients

NCT00996476

The purpose of this study is to evaluate effectiveness, safety and pharmacokinetics (Explores what the body does to the medication) of TMC435350 in combination with Peginterferon Alfa-2a and Ribavirin in genotype 1 hepatitis C virus infected Japanese participants who have never received treatment for their hepatitis C infection.

Hepatitis C, Chronic

Janssen Pharmaceutical K.K.92 participantsStarted Jul 2009

Amagasaki, Japan • Hiroshima, Japan • Kagoshima, Japan +16 more locations

COMPLETEDPhase 3

Phase 3 Study of Sofosbuvir and Ribavirin

NCT01497366

This study was to assess the safety and efficacy of sofosbuvir (GS-7977; PSI-7977) in combination with ribavirin (RBV) administered for 12 weeks compared with pegylated interferon (PEG)/RBV administered for 24 weeks in treatment-naive patients with Hepatitis C (HCV) genotype 2 or 3. Efficacy was assessed by the rate of sustained viral response (SVR) 12 weeks after the discontinuation of therapy (SVR12). This was a non-inferiority study, and if non-inferiority was demonstrated, the study was then allowed to test for superiority.

Hepatitis C

Gilead Sciences527 participantsStarted Dec 2011

Birmingham, Alabama, United States • Montgomery, Alabama, United States • Bakersfield, California, United States +94 more locations

A Study to Assess the Effectiveness, Safety, and Pharmacokinetics of TMC435 in Combination With Peginterferon Alfa-2a and Ribavirin in Hepatitis-C Infected Patients

Phase 3 Study of Sofosbuvir and Ribavirin

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