Hepatitis Clinical Trials

Showing 1401-1420 of 1,819 trials

An Open Label Study of the Effect of Telaprevir in Combination With Ribavirin and Peginterferon on HCV Infection in Stable Liver Transplant Patients

NCT01467505

To assess efficacy of telaprevir, pegylated interferon alfa-2a (Peg-IFN-alfa-2a), and ribavirin (RBV) for hepatitis C virus (HCV) in a 48-week total treatment duration regimen following liver transplantation.

Hepatitis C

Vertex Pharmaceuticals Incorporated61 participantsStarted Feb 2012

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Los Angeles, California, United States +19 more locations

UNKNOWNNA

Neurocognitive Performance and Emotional State in HCV Patients With IFN-free Antiviral Therapy

NCT02469012

The present study evaluates neurocognitive performance as well as measures of mood, quality of life, and fatigue in patients with chronic hepatitis C infection. In a prospective longitudinal study design, included patients are monitored before, during, and in the long-term follow-up of interferon-free antiviral treatment (Sofosbuvir +/-Daclatasvir +/- Ribavirin or Sofosbuvir/Ledipasvir +/- Ribavirin). Main study goals are to compare post therapy results of sustained virologic responders to corresponding pretreatment values as well as to historic interferon-treatment patients without virological response. It is expected that HCV-associated neuropsychiatric symptoms and neurocognitive impairment is - at least in part - reversible by the successful application of modern IFN-free antiviral medication.

Hepatitis C, Chronic

University of Wuerzburg30 participantsStarted Oct 2014

Burghausen, Bavaria, Germany

An Open Label Study of the Effect of Telaprevir in Combination With Ribavirin and Peginterferon on HCV Infection in Stable Liver Transplant Patients

Neurocognitive Performance and Emotional State in HCV Patients With IFN-free Antiviral Therapy

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