Depression Clinical Trials

Showing 1381-1400 of 1,725 trials

The Effect on Depressive Symptoms in ECF Residents With COPD

NCT00974246

The purpose of this study is to assess the effect of treatment with Advair Diskus on depression using the Cornell depression scale in COPD patients in the nursing home.

Chronic Obstructive Pulmonary DiseaseDepression

Valley Medical Research30 participantsStarted Oct 2009

Brooksville, Florida, United States • Centerville, Ohio, United States

COMPLETEDPhase 1

Mental Health Services for Foster and Adopted Children

NCT00056303

This study will determine the effectiveness of a relationship-based intervention in improving the interaction between caregivers and young children placed in their care.

Problem BehaviorsAttention Deficit Hyperactivity DisorderDepression

University of Delaware220 participantsStarted Dec 2002

Newark, Delaware, United States

COMPLETEDPhase 3

Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression

NCT01403662

Long-term studies have emphasized that depressive symptoms and episodes account for majority of the illness burden experienced by individuals with bipolar disorder (BD). Previous studies have shown that blood levels of proteins called pro-inflammatory cytokines are abnormal in individuals with bipolar depression. The investigators hypothesize that preventing the production or release of pro-inflammatory cytokines will result in improvement of depressive symptoms in individuals with bipolar depression. Minocycline is a medication that inhibits the activation of immune cells (i.e. microglia) in the brain and reduces the production of pro-inflammatory cytokines. Treatment with minocycline has been shown to have antidepressant-like effects in animal studies and improve symptoms of individuals with schizophrenia. In this study, minocycline (100 mg twice a day) will be administered for 8 weeks to determine if it is an efficacious antidepressant for individuals with bipolar depression.

Bipolar DisorderBipolar DepressionBipolar I Depression+1 more

University Health Network, Toronto29 participantsStarted Jul 2011

Toronto, Ontario, Canada

The Effect on Depressive Symptoms in ECF Residents With COPD

Mental Health Services for Foster and Adopted Children

Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression

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Transcranial Direct Current Stimulation for the Treatment of Bipolar Depression

Neuroimaging Predictors of Antidepressant Treatment Outcome

The Effect of Group Treatment for Depression: A Study of Metacognitive Therapy, Mindfulness and Support Groups

Computer-Assisted Cognitive-Behavioral Therapy for Adolescent Depression

The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives

Relapse Predicting Model for First Episode Depression

Lexapro for the Treatment of Traumatic Brain Injury (TBI) Depression & Other Psychiatric Conditions

Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life Depression

Problem Solving Education and Neonatal Intensive Care Unit (NICU) Mothers

Efficacy of an Online Program for the Treatment of Mild and Moderate Depression

Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine

Strategic Use of New Generation Antidepressants for Depression

Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder

A Trial on Metacognitive Training for Depression (D-MCT)