Depression Clinical Trials in Phoenix

Showing 21-40 of 147 trials

ALTO-100 in Bipolar Disorder With Depression (BD-D)

NCT06656416

The purpose of this study is to assess antidepressant efficacy differences between ALTO-100 and placebo during the Double-Blind period in patients with bipolar disorder I or II with current major depressive episode, when used adjunctively to a mood stabilizer and/or atypical antipsychotic, related to patient characteristics. Additionally, safety, tolerability, and efficacy will be assessed in a subsequent open label treatment period.

Bipolar Disorder I or II With a Major Depressive Episode

Alto Neuroscience200 participantsStarted Oct 2024

Chandler, Arizona, United States • Phoenix, Arizona, United States • Yuma, Arizona, United States +24 more locations

COMPLETEDPhase 2< 1 mile

A Biomarker-Guided, Randomized, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With TRD

NCT05113771

This study was conducted as a randomized, double-blind, placebo-controlled, multi-center Phase 2b study. Approximately 180 subjects with treatment resistant depression who meet all eligibility criteria will be enrolled. The primary endpoint is to demonstrate liafensine is superior to placebo in DGM4 positive patients with TRD.

Treatment Resistant Depression

Denovo Biopharma LLC197 participantsStarted Jun 2022

Huntsville, Alabama, United States • Phoenix, Arizona, United States • Garden Grove, California, United States +42 more locations

ALTO-100 in Bipolar Disorder With Depression (BD-D)

A Biomarker-Guided, Randomized, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With TRD

Depression Trials in Other Cities

A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD-202B)

Phase 2b Study of ALTO-100 in MDD

A Clinical Trial to Determine the Long-term Safety and Tolerability of an Investigational Drug in People With Major Depressive Episode Associated With Bipolar I Disorder (Bipolar I Depression).

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression

A Safety and Efficacy Study of JNJ26489112 in Patients With Treatment-Resistant Major Depressive Disorder

Pramipexole to Enhance Social Connections

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD)

The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)

ANC-501 in the Treatment of Adults With Major Depressive Disorder

[Study Evaluating the Efficacy and Safety of a Digital Therapeutic as an Adjunct to TAU in Postpartum Depression]

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

Affect Treatment for Depression and Anxiety (TAD Pilot)

RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

A Study to Assess Adverse Events of Fosigotifator (ABBV-CLS-7262) in Adults With Major Depressive Disorder

Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer

Other Conditions in Phoenix