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Clareo Health | Depression Clinical Trials in Philadelphia | 174 Studies

Clinical Trials DepressionPhiladelphia

Depression Clinical Trials in Philadelphia

Find 174 clinical trials for depression near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Depression trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 174 trials

CompletedA Study of Duloxetine in Major Depressive Disorder (MDD) and Associated Painful SymptomsThe purpose of this study is to find out if 60 mg of duloxetine given once a day by mouth for 8 weeks to patients diagnosed with major depressive disorder, who also report…NCT01000805·Beverly Hills, California and 36 others

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Data from ClinicalTrials.govTerms

RecruitingPsilocybin Intervention for Veterans Overcoming Treatment-Resistant DepressionThe purpose of this multi-site randomized controlled trial is to evaluate the efficacy and risks of psilocybin for the treatment of depression in U.S. military Veterans with and…NCT07226232·Birmingham, Alabama and 4 others

TerminatedA Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive DisorderThis is a 6-week, randomised, multicenter, double-blind, placebo controlled, fixed dose parallel group study to assess the efficacy and safety of orvepitant (30 and 60 mg/day)…NCT00880048·Phoenix, Arizona and 31 others

CompletedA Efficacy Study of PRX-00023 in Patients With Major Depressive DisorderThe purpose of this randomized, double-blind, placebo-controlled study is to assess the safety and efficacy of PRX-00023 in patients with major depressive disorder.NCT00448292·Mesa, Arizona and 20 others

RecruitingA Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderThe purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD.NCT06793397·Birmingham, Alabama and 78 others

CompletedStudy of 6(S)-5-MTHF Among Selective Serotonin Reuptake Inhibitor-Resistant Outpatients With Major Depressive DisorderThe purpose of the study is to test whether oral 6(S)-5-MTHF (Deplin) is safe and effective in relieving depression when it is added to standard kinds of antidepressants called…NCT00955955·San Diego, California and 5 others

CompletedA Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive DisorderThe primary purpose is to study the efficacy, safety, and tolerability of LY2216684 as an adjunctive treatment for participants with major depressive disorder (MDD), who were…NCT00840034·Birmingham, Alabama and 23 others

CompletedFunctional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort SyndromeThe objective of this study is to determine the time course of duloxetine efficacy on the symptoms of Major Depressive Disorder (MDD)and on the symptoms of Soft Tissue Discomfort…NCT01035073·Philadelphia, Pennsylvania

CompletedOpen-Label Safety Study of AXS-05 in Subjects With DepressionAn open-label, long-term, safety study of AXS-05 in patients with major depressive disorder (MDD), including treatment resistant depression.NCT04039022·Phoenix, Arizona and 50 others

CompletedEfficacy and Safety of Vortioxetine (Lu AA21004) in Treating Adults With Major Depressive DisorderThe purpose of this study is to determine the efficacy and safety of once daily vortioxetine (Lu AA21004) in adults with major depressive disorder.NCT00672958·Birmingham, Alabama and 32 others

CompletedStudy to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)To assess the efficacy of pimavanserin compared to placebo when given adjunctively to a selective serotonin reuptake inhibitor (SSRI)/serotonin-norepinephrine reuptake inhibitor…NCT03018340·Birmingham, Alabama and 35 others

CompletedA Study Comparing Duloxetine and Placebo in Assessing Energy and Vitality in Major Depressive Disorder (MDD) PatientsStudy F1J-US-HMFS comprises two identical multicenter, 9-month, randomized, placebo-controlled, double-blind, trials (HMFSa and HMFSb).NCT00536471·Beverly Hills, California and 46 others

Not yet recruitingOptimizing Stimulation Parameters for Electroconvulsive TherapyThe goal of this clinical trial is to improve how electroconvulsive therapy (ECT) stimulation settings are chosen.NCT07561307·Philadelphia, Pennsylvania

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal WomenDesvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI).NCT00369343·Birmingham, Alabama and 36 others

CompletedEfficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant TreatmentThe objectives of this 10-week study are to evaluate the efficacy, safety, and tolerability of AVP 786 as an adjunctive therapy compared with placebo in patients with major…NCT02153502·Birmingham, Alabama and 31 others

CompletedVA Augmentation and Switching Treatments for Improving Depression OutcomesThe overall purpose is to determine research based 'next-steps' for outpatients with major depressive disorder who have not had satisfactory outcomes to standard 'first-step'…NCT01421342·Tuscaloosa, Alabama and 34 others

CompletedA Study of Eszopiclone in Subjects With Insomnia Related to Major Depressive DisorderThe purpose of this study is to evaluate subjective sleep efficacy in subjects with insomnia related to major depressive disorder.NCT00368030·Birmingham, Alabama and 64 others

TerminatedA Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic FeaturesApproximately 450 patients will be randomized to receive mifepristone or placebo for 7 days followed by antidepressant.NCT00637494·Little Rock, Arkansas and 41 others

TerminatedA Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD)The purpose of this study is to assess the long-term safety and tolerability of aticaprant administered as adjunctive therapy to a current antidepressant (selective serotonin…NCT05518149·Birmingham, Alabama and 233 others

SuspendedPramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIVA phase II, randomized, open-label, two-arm clinical trial evaluating the safety and efficacy of pramipexole extended release (ER) versus escitalopram for the treatment of major…NCT06705478·Birmingham, Alabama and 40 others

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