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Clareo Health | Depression Clinical Trials in Chicago | 177 Studies

Clinical Trials DepressionChicago

Depression Clinical Trials in Chicago

Find 177 clinical trials for depression near Chicago, Illinois. Connect with research centers in your area.

All Depression trials nationwide All trials in Chicago

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 177 trials

TerminatedTreatment for Chronic DepressionThe purpose of this study is to test the clinical efficacy of two psychotherapies for early onset chronic major depression, including Behavioral Activation (Jacobson et al.…NCT00204152·Chicago, Illinois CompletedEfficacy and Safety of GLYX-13 in Subjects With Inadequate/Partial Response to AntidepressantsGLYX-13 is a NMDA receptor glycine site partial agonist being studied in subjects with major depressive disorder (depression) who have responded inadequately to another…NCT01684163·Birmingham, Alabama and 25 others

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Data from ClinicalTrials.govTerms

CompletedA Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive DisorderThe study is a Phase 2, double-blind, randomized, placebo-controlled study in Major Depressive Disorder (MDD) participants with an inadequate response to standard antidepressants…NCT06340958·La Jolla, California and 22 others

Enrolling by invitationAn Open-Label Study of Azetukalner in Major Depressive DisorderX-NOVA-OLE is a multicenter, open-label study to evaluate the long-term safety, tolerability, and efficacy of azetukalner as a monotherapy in adult participants who successfully…NCT06922110·Phoenix, Arizona and 70 others

CompletedVortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)The purpose of this study is to evaluate the efficacy of vortioxetine (5, 10, and 20 mg) versus placebo during the first 28 weeks of the 32-week double-blind treatment period in…NCT02371980·Phoenix, Arizona and 78 others

CompletedEEG Biomarkers for Predicting Response to Antidepressant TherapyThe purpose of this study is to evaluate the potential early EEG predictors of an individual's response to treatment with antidepressant medications.NCT00289523·Los Angeles, California and 9 others

CompletedA Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)The purpose of this study is to assess the socio-demographic, disease-related and treatment-related characteristics, and the standard of care (SOC) treatment patterns of…NCT05841030·Birmingham, Alabama and 94 others

TerminatedOpen-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE)This study is a multi-center, open-label trial to evaluate the long-term safety and efficacy of AXS-05 in subjects with major depressive disorder with prior treatment failuresNCT04634669·Little Rock, Arkansas and 19 others

CompletedA Long-Term Study of Aripiprazole in Patients With Major Depressive DisorderThis trial is a 52-week safety study to evaluate the safety of adjunctive aripiprazole in outpatients with major depressive disorder who have experienced an incomplete response to…NCT00095745·Mesa, Arizona and 57 others

CompletedSafety and Efficacy of Vortioxetine (Lu AA21004) in Adults With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy, safety and tolerability of vortioxetine, once daily (QD), compared with placebo in adults with major depressive disorder.NCT01153009·Beverly Hills, California and 55 others

CompletedA Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an…NCT04688164·Miami, Florida and 10 others

CompletedA Safety and Effectiveness Study of JNJ-18038683 in Patients With Moderate to Severe DepressionThe purpose of this study is to evaluate the safety and effectiveness of JNJ-18038683 compared to escitalopram and placebo in patients with moderate to severe depression.NCT00566202·Little Rock, Arkansas and 25 others

TerminatedOpen Label Extension for GLYX13-C-202, NCT01684163Examine the safety of long term repeat exposure to GLYX-13 in subjects who participated in GLYX13-C-202.NCT02192099·Birmingham, Alabama and 9 others

WithdrawnN2O for Acute Suicidality and Depression in the EDInvestigators are conducting this double-blind, randomized control trial (RCT), to compare inhaled N2O+ treatment as usual (TAU) versus inhaled placebo+TAU; demonstrating the…NCT05710887·Chicago, Illinois

CompletedA Study of Adjunctive Aripiprazole in Patients With Major Depressive DisorderThis trial is a 14 week, randomized, double-blind, placebo controlled study, to assess the safety and efficacy of aripiprazole as adjunctive treatment to an ongoing antidepressant…NCT00095823·Garden Grove, California and 19 others

Enrolling by invitationPhase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)This is a long- term extension of the double-blind trials APPROACH (CYB003-002) and EMBRACE (CYB003-003).NCT06605105·Phoenix, Arizona and 48 others

CompletedMaintenance NeuroStar Transcranial Magnetic Stimulation (TMS) in Patients With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy of scheduled maintenance Transcranial Magnetic Stimulation (TMS) treatment compared to on-demand TMS treatment for…NCT01415154·Chicago, Illinois and 5 others

CompletedA Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive DisorderThe purpose of this study is to determine if TC-5214 or placebo (a tablet that looks like medicine tablet or capsule, but contains no active medicine) is safe and effective when…NCT01152554·Birmingham, Alabama and 93 others

RecruitingA Randomized Study of Azetukalner Versus Placebo in Major Depressive DisorderX-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy…NCT06775379·Phoenix, Arizona and 50 others

TerminatedTreatment of Depression With QuetiapineThe purpose of this study is to examine the mood stabilizing and antipsychotic properties of quetiapine in the treatment of depression by comparing subjects who were randomly…NCT00174603·Chicago, Illinois

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