Depression Clinical Trials in Chicago

Showing 61-80 of 229 trials

What SSI Duration is Most Effective? An Online Experiment With American Adults

NCT06313736

In a previous study (https://osf.io/qdznc), the research team found that an 8-minute version of a single-session intervention for loneliness was more effective than a 23-minute version of it. The present work aims to further explore the relationship between intervention duration and effectiveness. In this online trial, participants will be randomized to a 15-minute single-session depression intervention called the Action Brings Change (ABC) Program, a 10-minute version of it, a 6-minute version of it, or a 2-minute version of it. The main analysis will evaluate how change in depressive symptoms over eight weeks differs across conditions.

Depression

Northwestern University1,145 participantsStarted Mar 2024

Chicago, Illinois, United States

TERMINATEDPhase 22.2 miles

Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)

NCT04663321

The main purpose of this study is to assess the efficacy and safety of daily and intermittent dosing of MK-1942 compared to placebo among participants with Treatment-Resistant Depression (TRD) on a stable course of antidepressant therapy. The dual primary hypotheses of the study are that the daily MK-1942 treatment or intermittent MK-1942 treatment are superior to placebo in reducing Montgomery-Asberg Depression Rating Scale (MADRS) score.

Treatment Resistant Depression

Merck Sharp & Dohme LLC99 participantsStarted May 2021

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Little Rock, Arkansas, United States +42 more locations

What SSI Duration is Most Effective? An Online Experiment With American Adults

Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)

Depression Trials in Other Cities

A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)

Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD

Integrating a Suite of Mental Health Apps for Depression in a Healthcare Setting

Prenatal Depression Prevention Effects on Parenting and Young Child Self-Regulation and Functioning

Positive Affect Regulation sKills at Northwestern University

The "PC-LIGHT" Study

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Testing Different Modes of Cognitive Behavior Therapy

A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder

A Study to Evaluate the Efficacy of SAGE-217 in the Treatment of Adult Participants With Major Depressive Disorder

A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

Medibio DDA Confirmatory Performance Study

Optimizing Outcomes of Treatment-Resistant Depression in Older Adults

Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

Lay-Delivered Behavioral Activation in Senior Centers

Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)

Other Conditions in Chicago