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Clareo Health | COPD Clinical Trials in Philadelphia | 184 Studies

Clinical Trials COPDPhiladelphia

COPD Clinical Trials in Philadelphia

Find 184 clinical trials for copd near Philadelphia, Pennsylvania. Connect with research centers in your area.

All COPD trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 184 trials

CompletedCo-administration of Olodaterol Respimat® and Tiotropium Handihaler®The overall objective of this study is to assess efficacy and safety of 12 weeks, once daily, orally inhaled co-administration of olodaterol 5 µg (delivered by the Respimat®…NCT01696058·Anniston, Alabama and 93 others

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Data from ClinicalTrials.govTerms

CompletedA Phase 2a Study to Assess Safety, Daily Symptoms, PK, and Biomarkers of YPL-001 in COPD PatientsThis is a Phase 2a, proof-of-concept, multicenter, randomized, double-blind, double dummy, 3-treatment, parallel study, with low and high YPL 001 doses (low dose and high dose…NCT02272634·Birmingham, Alabama and 3 others

CompletedA Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPDThe primary objective of this study is to compare the effects of orally inhaled tiotropium + olodaterol fixed dose combination (2.5/5 µg; 5/5 µg) with placebo on exercise…NCT01525615·Torrance, California and 59 others

TerminatedLung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) StudyMulticenter, randomized, assessor-blinded controlled study of safety and effectiveness of the PneumRx, Inc. RePneu Lung Volume Reduction Coil (RePneu LVRC) SystemNCT01608490·Birmingham, Alabama and 28 others

CompletedValidation of a New Shortness of Breath With Daily Activities Questionnaire in Patients With Chronic Obstructive Pulmonary DiseaseThe purpose of this study is to evaluate a new questionnaire to capture the patient experience of COPD.NCT00984659·Jasper, Alabama and 38 others

RecruitingSTRIVE Post-Market Registry StudyThis is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe…NCT04302272·Phoenix, Arizona and 15 others

TerminatedA 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)The purpose of the study is to evaluate the efficacy and safety of two doses of CHF6001 (Tanimilast), as add-on to maintenance triple therapy in the target patient population.NCT04636801·Sheffield, Alabama and 446 others

CompletedA Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a Next-Generation Propellant in Participants 40 to 80 Years of Age With COPDThe purpose of this study is to demonstrate that the lung function effect from orally inhaled BGF delivered via HFO propellant is equivalent to the lung function effect from…NCT06075095·Sheffield, Alabama and 86 others

CompletedEvaluation of the Spiration® Valve System for Emphysema to Improve Lung FunctionEMPROVE is a multicenter, prospective, randomized, controlled study designed to evaluate the safety and long-term effectiveness of the Spiration Valve System in patients with…NCT01812447·Fort Smith, Arkansas and 33 others

CompletedComparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to Severe Exacerbations in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease.The overall objective is to assess the effect of once daily tiotropium + olodaterol fixed dose combination compared to 5 µg tiotropium (both delivered with the Respimat® inhaler)…NCT02296138·Andalusia, Alabama and 817 others

CompletedComparing Two Pneumococcal Vaccines in Adults With Chronic Obstructive Pulmonary DiseasePneumococcal disease is a serious bacterial infection that can affect different parts of the body, including the lungs.NCT00457977·Birmingham, Alabama and 17 others

TerminatedA Study to Evaluate Biomarkers in Chronic Obstructive Pulmonary DiseaseThe primary objective of this study is to identify biomarkers that can be used for evaluation of efficacy in subjects presenting with AECOPDNCT01268072·Baltimore, Maryland and 9 others

CompletedEfficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD); (PINNACLE 1)The overall objective of this study is to assess the efficacy and safety of treatment with PT003 (GFF MDI), PT005 (FF MDI), PT001 (GP MDI), and open-label tiotropium bromide…NCT01854645·Andalusia, Alabama and 138 others

TerminatedA Study Designed to Evaluate ODSH in Subjects With Exacerbations of COPDThe purpose of this study is to determine whether ODSH, when added to conventional treatment, is more effective in treating COPD exacerbations than conventional therapy alone.NCT00457951·Orange, California and 37 others

CompletedSmoking Cessation in Subjects With Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD).This study is to be conducted in subjects with mild-to-moderate COPD who are cigarette smokers with the intent of demonstrating differences in smoking cessation between…NCT00285012·Birmingham, Alabama and 31 others

TerminatedA Pilot Study of Danirixin for Disease Progression in Chronic Obstructive Pulmonary Disease (COPD)This is a pilot study to investigate the effect of danirixin hydrobromide 35 milligram (mg) tablets on lung function and health related quality of life (HRQoL) in subjects with…NCT03170232·Birmingham, Alabama and 10 others

TerminatedVector Efficacy Cross-Over Pilot StudyThe study evaluates the safety and efficacy of the modified Bi-level positive airway pressure (BiPAP) A40 with Vector Algorithm to treat Chronic Obstructive Pulmonary Disease…NCT04263532·Philadelphia, Pennsylvania

CompletedStudy to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)Impaired physical function and muscle dysfunction are a major consequence of COPD, which may be associated with increased mortality, poor quality of life and increased health care…NCT03359473·Torrance, California and 10 others

RecruitingEvaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPDThe dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care.NCT07051707·Birmingham, Alabama and 9 others

RecruitingFeasibility of Semaglutide in Advanced Lung DiseaseThe goal of this clinical trial is to learn whether semaglutide, an FDA-approved treatment for diabetes and obesity, is feasible and tolerable in patients with advanced lung…NCT05746039·Philadelphia, Pennsylvania

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