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Clareo Health | Colorectal Cancer Clinical Trials in Boston | 363 Studies

Clinical Trials Colorectal CancerBoston

Colorectal Cancer Clinical Trials in Boston

Find 363 clinical trials for colorectal cancer near Boston, Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Boston

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 21-40 of 363 trials

TerminatedStudy of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D MutationA Phase 1/2 study of MRTX1133 in solid tumors harboring a KRAS G12D mutation.NCT05737706·Phoenix, Arizona and 13 others CompletedProspective Analysis of Hypersensitivity Reactions to OxaliplatinThis research study will examine how often hypersensitivity, or allergic reactions, occur in patients receiving the chemotherapy medication oxaliplatin.NCT00831571·Boston, Massachusetts TerminatedA Study of SGN-STNV in Advanced Solid TumorsThis trial will look at a drug called SGN-STNV to find out whether it is safe for patients with solid tumors. It will study SGN-STNV to find out what its side effects are.NCT04665921·Los Angeles, California and 17 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid TumorsThe main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally advanced or metastatic solid…NCT06607185·Birmingham, Alabama and 44 others

RecruitingA Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal CancerThe purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of…NCT07284849·Mobile, Alabama and 296 others

CompletedEducational Intervention With or Without Telephone Counseling in Increasing Colorectal Cancer Screening Compliance in Brothers and Sisters of Patients With Colorectal CancerRATIONALE: Printed educational materials and counseling by telephone may improve colorectal cancer screening compliance in brothers and sisters of patients with colorectal cancer.NCT00352638·Newark, Delaware and 17 others

CompletedPembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid TumorsThis is an open-label, multicenter, Phase 1b platform study in subjects with advanced or metastatic solid tumors (Part 1a) and subjects with selected solid tumors (Part 1b and…NCT02646748·San Francisco, California and 16 others

CompletedA Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer TreatmentThis is a three-part study of NUC-3373 administered by intravenous (IV) infusion across two administration schedules, either as monotherapy or as part of various combinations with…NCT03428958·Boston, Massachusetts and 9 others

TerminatedCombination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006015·Birmingham, Alabama and 46 others

Active not recruitingA Study of Novel Study Interventions and Combinations in Participants With Colorectal CancerThe main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC).NCT06792695·Scottsdale, Arizona and 55 others

TerminatedA Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid TumorsThis study will test the safety of a drug called PF-08046049/SGN-BB228 in participants with melanoma and other solid tumors that are hard to treat or have spread through the body.NCT05571839·Los Angeles, California and 36 others

CompletedStudy of Vitamin D in Untreated Metastatic Colorectal CancerThis is a prospective, randomized, double-blind phase II trial to evaluate the efficacy and safety of two doses of vitamin D supplementation in combination with standard…NCT01516216·Boise, Idaho and 17 others

CompletedSample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD)The primary objective of this study is to gather stool samples from subjects with inflammatory bowel disease (IBD) to be added to a test set of stool samples that will be utilized…NCT02503696·Dothan, Alabama and 28 others

RecruitingA Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid TumorsThis is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent…NCT03526835·La Jolla, California and 53 others

CompletedColorectal Cancer Screening for Cancer SurvivorsThe risk of colorectal cancer (CRC) is significant among cancer survivors treated with abdominal radiation therapy (RT).NCT00982059·Boston, Massachusetts and 1 other

Active not recruitingStudy of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid TumorsThis is a multicenter Phase 1b, open-label study to assess safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of cabozantinib taken in combination with…NCT03170960·Gilbert, Arizona and 123 others

Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

CompletedImpact of a Patient-Centered Program for Low Anterior Resection Syndrome a Multicenter Randomized Controlled TrialAfter undergoing restorative proctectomy for rectal cancer, many patients are left with significant bowel dysfunction, known as Low Anterior Resection Syndrome (LARS).NCT03828318·Boston, Massachusetts and 5 others

TerminatedStudy of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced MalignanciesA first-in-human study using BDC-3042 as a single agent and in combination with cemiplimab in patients with advanced malignanciesNCT06052852·Palo Alto, California and 5 others

CompletedCOM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.This is a Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary clinical activity of COM701 as monotherapy…NCT03667716·Los Angeles, California and 10 others

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