Clinical Trials in Salt Lake City

Showing 10461-10480 of 14,325 trials

Study of Mocetinostat in Patients With Urothelial Carcinoma Having Inactivating Alterations of Specific Genes

NCT02236195

Mocetinostat is an orally administered histone deacetylase (HDAC) inhibitor. This study is a Phase 2 trial evaluating the efficacy of mocetinostat in patients that have advanced urothelial carcinoma that has specific changes in tumor genes. Patients must have previously received treatment with chemotherapy that included a "platinum-containing agent" such as cisplatin. The study will enroll in stages, with 15 patients in the first stage. More patients will be added to the study if enough patients having beneficial responses are observed. Mocetinostat will be administered using oral capsules three times each week (eg, Monday, Wednesday and Friday). The study is designed to evaluate whether the number of patients responding to treatment is substantially higher than would be expected with other available treatments.

Urothelial Carcinoma

Mirati Therapeutics Inc.17 participantsStarted Oct 2014

Birmingham, Alabama, United States • Duarte, California, United States • Fort Myers, Florida, United States +11 more locations

COMPLETEDPhase 2< 1 mile

Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma

NCT00511238

To evaluate the overall response rate and safety and tolerability of carfilzomib in subjects with relapsed and refractory multiple myeloma. Patients must have received prior treatment with bortezomib and either thalidomide or lenalidomide and be refractory to their last treatment.

Multiple Myeloma

Amgen312 participantsStarted Aug 2007

Mobile, Alabama, United States • Scottsdale, Arizona, United States • Beverly Hills, California, United States +31 more locations

Study of Mocetinostat in Patients With Urothelial Carcinoma Having Inactivating Alterations of Specific Genes

Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma

Find Trials by Condition in Salt Lake City

Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

A Safety And Efficacy Study of Ibuprofen 250 mg / Acetaminophen 500 mg In The Treatment Of Post-Surgical Dental Pain

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Efficacy and Safety of FTY720 in Patients Who Receive a Kidney Transplant

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Adult-to-Adult Living Donor Liver Transplantation Study

Investigation of Sacroiliac Fusion Treatment (INSITE)

Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions

Dasotraline Adult ADHD Study

Study to Investigate the Safety and Efficacy of Tregalizumab in Subjects (MTX-IR) With Active Rheumatoid Arthritis

The Safety and Efficacy of vBloc Therapy Delivered by the Maestro Rechargeable System for the Treatment of Obesity

Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support

Registry Trial to Determine pCLE Image Interpretation Criteria and Preliminary Accuracy in the Lung

Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Safety Study of PLX4032 in Patients With Solid Tumors

Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias

A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died

Safety and Immunogenicity of Norovirus Bivalent Virus-Like Particle Vaccine in Healthy Adults