Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mauna Kea Technologies
The primary aim of this study is to develop the criteria to differentiate healthy versus diseased tissue in patient with discrete lung lesions or to characterize acute lung rejection in patients with transplanted lungs. Once these criteria have been defined, the diagnostic parameters and the reproducibility of pCLE will be assessed.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female \> 18 years of age
Willing and able to comply with study procedures and provide written informed consent to participate in the study
Indeterminate discrete nodule(s) suspicious for cancer scheduled for diagnostic bronchoscopy
Newly discovered \&/or prior discovered non classified nodules, hard to define based on CT scan
Purpose of bronchoscopy is for diagnosis of lesion(s) - can be solitary pulmonary nodule or multiple lesions
All lesion locations are acceptable
Any patient undergoing clinically indicated bronchoscopies after lung transplantation
Patients post transplant showing clinical signs of acute rejection \>3 weeks; \< 1 year
Patient with single or double lung transplant
You may not be if
Contraindication to short-acting anesthetic agents;
Contraindications to transbronchial biopsy
Bleeding diathesis;
A pacemaker/defibrillator;
A diagnosis by other means (sputum cytology, microbiology).
Unwilling To Consent
Unable To Safely Tolerate A Bronchoscopic Procedure
Unwilling To Comply With Surveillance Bronchoscopy Follow Up
Chronic Rejection
Fungal Disease
Ax Histological Assessment Or Incomplete Biopsy Procedure Should Be Considered As A Screen Failure
Clareo Health | Registry Trial to Determine pCLE Image Interpretation Criteria and Preliminary Accuracy in the Lung
