Clinical Trials in Philadelphia

Showing 1141-1160 of 20,904 trials

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

NCT06789445

Study OpCT-001-101 is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in approximately 54 adults with primary photoreceptor (PR) disease. Phase 1 focuses on safety and features a dose-escalation design. Phase 2 is designed to gather additional safety data and assess the effect of OpCT-001 on measures of visual function, functional vision, and anatomic measures of engraftment in different clinical subgroups.

Primary Photoreceptor DiseaseRetinitis Pigmentosa (RP)Usher Syndrome+6 more

BlueRock Therapeutics54 participantsStarted Mar 2025

Miami, Florida, United States • Philadelphia, Pennsylvania, United States • Dallas, Texas, United States +1 more locations

AVAILABLE< 1 mile

Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome

NCT05795361

As the HGT-HIT-046 (NCT01506141) and SHP609-302 (NCT02412787) studies are completed and closed, this post-trial access (PTA) program provides TAK-609 to participants in these studies for whom the benefit:risk ratio of continued treatment with idursulfase-IT remains positive.

Hunter Syndrome

Takeda

Phoenix, Arizona, United States • Oakland, California, United States • Wilmington, Delaware, United States +19 more locations

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome

Find Trials by Condition in Philadelphia

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis

Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib)

A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)

A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors

Micro-UltraSound In Cancer - Active Surveillance

Registry Study for the Evaluation of High-risk Cardiac Patients by WILLEM AI-based ECG Platform