Clinical Trials in Philadelphia

Showing 1141-1160 of 9,968 trials

Integrating Community Health Workers Into the Care of Children With Type 1 Diabetes

NCT03475108

The primary aim of this randomized controlled trial is to determine if the integration of a Community Health Worker into the healthcare team is associated with an improvement in diabetes control in children with type 1 diabetes. The secondary objectives are to determine if utilization of Community Health Workers is also associated with reduced emergency department visits and hospitalizations, improved attendance at outpatient diabetes appointments, and improvements in psychosocial outcomes and diabetes control.

Type 1 Diabetes MellitusPsychosocial ProblemCompliance, Patient+1 more

Children's Hospital of Philadelphia84 participantsStarted Apr 2018

Philadelphia, Pennsylvania, United States

RECRUITINGPhase 1/2< 1 mile

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

NCT04811560

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D\[s\]) of bleximenib in phase 1 Part 1 (Dose Escalation) and to determine the safety and tolerability at RP2D in Phase 1 Part 2 (Dose expansion). The purpose of the Phase 2 part of the study is to evaluate the efficacy of bleximenib at the RP2D.

Acute LeukemiasAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia

Janssen Research & Development, LLC400 participantsStarted May 2021

Goodyear, Arizona, United States • Duarte, California, United States • Orange, California, United States +98 more locations

Integrating Community Health Workers Into the Care of Children With Type 1 Diabetes

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

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Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Rocket Study: A Study to Characterize Biomarkers and Disease Progression in Participants With Pelizaeus-Merzbacher Disease

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

855303-RNA Biomarker Validation

Novel Endoscopic Bite Block

Safety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

CROSSOVER STUDY OF ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR

Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Perf-Fix Study for Chronic Tympanic Membrane Repair

PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System

Prevention of Injury in Skilled Nursing Facilities Through Optimizing Medications

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Evaluation of the Efficacy and Safety of Magnetic Resonance Angiography (MRA) Using Gadopiclenol Compared to Gadoterate Meglumine in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease

A Study to Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP)