Clinical Trials in Philadelphia

Showing 3541-3560 of 15,860 trials

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year

NCT03293524

The goal of this clinical trial is to assess the safety and efficacy of GS010, a gene therapy, in improving the retina functional \& structural outcomes in subjects with LHON due to the G11778A ND4 mitochondrial mutation when vision loss duration is present up to one year.

Leber Hereditary Optic Neuropathy

GenSight Biologics98 participantsStarted Mar 2018

Pasadena, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +10 more locations

RECRUITING< 1 mile

Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

NCT04199000

The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.

Congenital Disorders of Glycosylation

Icahn School of Medicine at Mount Sinai500 participantsStarted Oct 2019

San Diego, California, United States • Aurora, Colorado, United States • Jacksonville, Florida, United States +9 more locations

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year

Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

Find Trials by Condition in Philadelphia

Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML

Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction

A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)

A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

ERG Components in Schizophrenia and Bipolar Disorder Type I

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers

A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer

Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS)

A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Life-Steps Counseling to Enhance Adherence and Engagement in PrEP Care

A Clinical Study on Acuris™ - Conometric Concept for Single Tooth Restoration