Clinical Trials in Philadelphia

Showing 3561-3580 of 20,904 trials

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

NCT06108050

This Phase 1 first-in-human study will investigate the safety, tolerability, pharmacokinetics (PK), immunogenicity, and preliminary antitumor activity of JZP898 monotherapy as well as JZP898 in combination with pembrolizumab in adult participants with advanced or metastatic solid tumors.

Advanced Solid TumorMetastatic Solid Tumor

Jazz Pharmaceuticals177 participantsStarted Nov 2023

Encinitas, California, United States • Fresno, California, United States • Denver, Colorado, United States +7 more locations

COMPLETEDPhase 3< 1 mile

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

NCT04594369

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

Non-Cystic Fibrosis Bronchiectasis

Insmed Incorporated1,767 participantsStarted Dec 2020

Birmingham, Alabama, United States • Conway, Arkansas, United States • Little Rock, Arkansas, United States +370 more locations

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

Find Trials by Condition in Philadelphia

Gamification and Physical Activity in PD

Sequential Multiple Assignment Randomized Trial for Bipolar Depression

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

BHV-7000 Open-Label Extension Bipolar Mania Study

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014)

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

A Study of the Drugs Talazoparib and Temozolomide in Prostate Cancer

A Mobile Health Intervention Among Hispanics

A Study of Pembrolizumab in People With Ultra-Rare Sarcomas

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

A Registry to Gather Real World Use Data on the Cerene® Cryotherapy Device

A Study to Evaluate the Safety and Immunogenicity of the V3-region Directed Immunogens DV700P-RNA Followed by DV701B1.1-RNA in Adults Without HIV

HOPE Against Cancer Recurrence in HCC

Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation