Capravirine (AG1549) in Combination With Viracept and Two NRTIs in HIV Infected Patients Who Failed an Initial NNRTI Containing Regimen

Inclusion Criteria

• •Male or female at least 18 years old
• •HIV RNA level \>1000 copies/mL at screening
• •CD4 \>50 cells/uL at screening
• •Patient is currently taking a regimen that includes an NNRTI plus 2 NRTIs for at least 28 days and is currently failing this regimen
• •Patient has adequate hematology tests (absolute neutrophil count \>1000/uL, Platelets\>75,000uL, hemoglobin 9g/L)
• •Patient has adequate renal function (serum creatinine of \<1.5 upper limit of normal)
• •Patient has adequate liver function (AST, ALT, and bilirubin \< 2.5 upper limit of normal)