Clinical Trials in Philadelphia

Showing 3261-3280 of 20,904 trials

HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancer

NCT03685331

The main purpose of this research study is to learn whether the investigational combination of olaparib, palbociclib, and fulvestrant is safe in patients with estrogen receptor-positive breast cancer and BRCA1 or BRCA2 mutations.

Metastatic Breast CancerLocally Advanced Breast CancerAdvanced Breast Cancer+2 more

Abramson Cancer Center at Penn Medicine9 participantsStarted Oct 2020

Philadelphia, Pennsylvania, United States

COMPLETEDNA< 1 mile

Exploring Multiple Self-Help Interventions to Promote Self-Efficacy and Overcome Disability

NCT06646757

EMPOWER-IBD aims to identify behavioral interventions to strengthen patients' self-efficacy for self-management as a mechanism to reduce IBD-related disability. This multisite, randomized controlled trial with 16 arms will randomize adults with moderate-to-severe IBD-related disability to a combination of four multimodal behavioral interventions to test their clinical effectiveness in reducing IBD-related disability and improving self-efficacy. The interventions are four existing, publicly available disease-specific self-help resources offered at no cost to the participants: a book, smart app, help center, and peer mentor. Participants will complete online surveys and may engage in virtual focus groups. Participants may receive an honorarium (e-gift card) and/or be entered into a lottery for a giftcards post-survey completion and focus group participation.

Ulcerative Colitis (UC)Crohn Disease (CD)

University of Pennsylvania803 participantsStarted Aug 2024

Philadelphia, Pennsylvania, United States

HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancer

Exploring Multiple Self-Help Interventions to Promote Self-Efficacy and Overcome Disability

Find Trials by Condition in Philadelphia

Menstrual Cycle TMS Plasticity Pilot

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

Neuronavigated aiTBS for TRD

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

Supporting Parents in Affirming Their Children's Experiences of Stigma

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors