Clinical Trials in Philadelphia

Showing 3281-3300 of 20,904 trials

Autoimmunity After Checkpoint Blockade

NCT04119713

The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint inhibitor therapy to develop an immune-related adverse event (irAE).

AutoimmunityCancerImmunotoxicity+1 more

Abramson Cancer Center at Penn Medicine600 participantsStarted Feb 2020

Philadelphia, Pennsylvania, United States

RECRUITING< 1 mile

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

NCT04071847

The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.

Movement DisordersParkinson DiseaseEssential Tremor+4 more

Abbott Medical Devices1,000 participantsStarted Nov 2019

Tucson, Arizona, United States • Los Angeles, California, United States • Sacramento, California, United States +45 more locations

Autoimmunity After Checkpoint Blockade

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Find Trials by Condition in Philadelphia

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia

A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma

MyStroke for Stroke Survivors and Caregivers

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

Rehab CARES In USA: Clinical Trial

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

A Study Comparing Geriatric Co-Management With Geriatric Guided Supportive Care in Older Patients Receiving Chemoradiation Therapy for Their Head and Neck Cancer

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

Investigation of the Two Level Simplify® Cervical Artificial Disc

Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial Disc

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors

A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors