Erlotinib, Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer

Exclusion Criteria

• •Significant history of cardiac disease unless the disease is well controlled
• •Active or uncontrolled infections or serious illness or medical conditions that could interfere with the patient's ongoing participation in study
• •History of any psychiatric condition that might impair the patient's ability to understand or to comply with the requirements of the study or to provide informed consent
• •History of smoking within the previous 14 days before enrollment or positive cotinine test at baseline
• •Pregnant or breast-feeding females
• •Symptomatic brain metastases that are not stable, that require steroids, that are potentially life-threatening, or that have required radiation within the last 14 days
• •History of allergic reactions attributed to compounds of similar chemical or biological composition to the study drugs