Clinical Trials in Cleveland

Showing 841-860 of 9,497 trials

Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis

NCT03375047

This Phase 1/2, first-in-human study evaluated the safety and tolerability of single and multiple escalating doses of MRT5005 administered by nebulization to the respiratory tract of adult subjects with cystic fibrosis (CF).

Cystic Fibrosis

Sanofi42 participantsStarted May 2018

Birmingham, Alabama, United States • Denver, Colorado, United States • Gainesville, Florida, United States +13 more locations

RECRUITINGPHASE1/PHASE290 miles

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

NCT06128551

This study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated solid tumors.

Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma

Revolution Medicines, Inc.534 participantsStarted Nov 2023

Duarte, California, United States • Orange, California, United States • Sacramento, California, United States +50 more locations

Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Find Trials by Condition in Cleveland

A Study of Barzolvolimab in Patients With Atopic Dermatitis

A Prospective Sub-Study of the Global Hypophosphatasia Registry

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Galleri® in the Medicare Population.

A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS)

Global Registry for Endovascular Aortic Treatment (GREAT)

Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease

Study of ATX-01 in Participants With DM1

A Long-Term Follow-Up Basket Study for Participants Treated With SynKIR Chimeric Antigen Receptor (CAR) T Cell Product

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

Comparing the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous (SC) Presentations

Intermuscular Coherence as a Biomarker for ALS

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

EMUs: Enhanced Monitoring Using Sensors After Surgery