Clinical Trials in Cleveland

Showing 861-880 of 9,497 trials

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

NCT06129747

The standard treatment for participants whose cancer has returned after breast conserving surgery is radiation given twice daily (separated by at least 6 hours) for a total of 30 treatments. The purpose of this study is to find out if giving radiation once a day for 15 treatments after repeat breast conserving surgery works as well as giving it the standard way.

Breast CancerTumor, Breast

Case Comprehensive Cancer Center55 participantsStarted Nov 2023

Cleveland, Ohio, United States • Cleveland, Ohio, United States

COMPLETEDPHASE3< 1 mile

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

NCT00066690

RATIONALE: Estrogen can stimulate the growth of breast tumor cells. Ovarian function suppression combined with hormone therapy using tamoxifen or exemestane may fight breast cancer by reducing the production of estrogen. It is not yet known whether suppression of ovarian function plus either tamoxifen or exemestane is more effective than tamoxifen alone in preventing the recurrence of hormone-responsive breast cancer. PURPOSE: This randomized phase III trial studies ovarian suppression with either tamoxifen or exemestane to see how well they work compared to tamoxifen alone in treating premenopausal women who have undergone surgery for hormone-responsive breast cancer.

Estrogen Receptor Positive Breast CancerProgesterone Receptor Positive TumorRecurrent Breast Carcinoma+5 more

ETOP IBCSG Partners Foundation3,066 participantsStarted Dec 2003

Birmingham, Alabama, United States • Anchorage, Alaska, United States • Scottsdale, Arizona, United States +497 more locations

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Find Trials by Condition in Cleveland

Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)

A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight

Registry of the Patient Experience for Carpal Tunnel Release

A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

A Longitudinal Observational Study of the Natural History and Management of Patients With HCC

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

A Study to Learn About the Study Medicine Called PF-07976016 in Adults With Obesity

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH

FX Shoulder Prospective Clinical Study

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

CLOZAPINE Response in Biotype-1

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer

A Study to Assess Recovery and Survival of Radiolabeled Apheresis Platelet Components Treated With the INTERCEPT Blood System for Platelets With LED Illuminator.

Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2

Pertuzumab, Trastuzumab, Hyaluronidase-zzxf and Enzalutamide for Treatment of Metastatic Castration-Resistant Prostate Cancer