Clinical Trials in Cleveland

Showing 821-840 of 19,775 trials

Magnesium as an Adjuvant Agent for Postoperative Pain

NCT05947760

Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO). This research study is looking at if using IV magnesium during surgery can help to reduce pain after surgery.

Pain, Postoperative

University Hospitals Cleveland Medical Center50 participantsStarted Mar 2025

Cleveland, Ohio, United States

COMPLETEDPhase 2< 1 mile

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

NCT05551273

The study aims to assess safety and tolerability of oral toll-like receptor (TLR) 8 agonist Selgantolimod (SLGN) administered for 24 weeks in participants with both CHB and HIV who have been receiving suppressive antiviral therapy for both viruses for ≥5 years and have qHBsAg level \>1000 (3 log10) IU/mL at screening. The study will also evaluate if TLR8 stimulation with SLGN will reduce hepatitis B surface antigen (HBsAg) titers in the blood.

Hepatitis BHIV Infections

National Institute of Allergy and Infectious Diseases (NIAID)29 participantsStarted May 2023

Birmingham, Alabama, United States • San Diego, California, United States • Atlanta, Georgia, United States +23 more locations

Magnesium as an Adjuvant Agent for Postoperative Pain

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

Find Trials by Condition in Cleveland

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A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment

A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

TLN-372 in Advanced KRAS Mutant Solid Tumors

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

IVIG for Infection Prevention After CAR-T-Cell Therapy

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

Impact of COL7A1 Gene Therapy on SCC Recurrence in RDEB Skin